Most people think performance improves by pushing harder. More intensity, more volume, more effort, more stimulation. That belief makes sense because intensity is visible. You can see heavy weights, fast running, deep breathing, sweat, and fatigue. What you cannot see is what actually determines whether the body adapts or breaks down. That hidden factor is how well the body handles transitions. Biology does not reward force. It rewards coordination. At every level of the body, from a single cell to the entire nervous system, health and performance depend on how smoothly systems shift from one state to another. These shifts include rest to effort, effort to recovery, fed to fasted, stress to calm, inflammation to healing, and sleep to wakefulness. The quality of these transitions determines whether the system becomes stronger or weaker over time. A transition in biology is any moment when demand changes faster than structure can adapt. When exercise begins, muscles suddenly require more energy. When exercise stops, energy demand suddenly drops. When food is eaten, nutrients flood the bloodstream. When fasting occurs, energy must be mobilized internally. When stress hormones rise, immune and metabolic priorities shift. These changes are not steady states. They are moments of adjustment, and they are where the system is most vulnerable. Most people misunderstand how energy works in the body. Energy is not something you simply have or run out of. Energy is controlled flow. At the cellular level, this flow is managed by mitochondria. Mitochondria are often called powerhouses, but a better way to understand them is as traffic controllers. Their job is not just to make energy, but to regulate how electrons move through a tightly controlled system. Electrons enter mitochondria from the breakdown of food and stored fuels. These electrons move through a series of protein complexes called the electron transport chain. As electrons move through this chain, energy is released in a controlled way to produce ATP, the molecule used to perform work. ATP is not the goal. It is the result of proper electron flow. When electron flow is smooth, energy production is clean and signaling is preserved. When electron flow becomes congested, problems arise.

I just got some and would like to know what a good starting dose is as a general mitochondrial dose.

From my own log here recently Wakeup 6am 1min Ice cold shower Fasted oral BPC-157, KPV, SLU-PP-332 on training days, fatty 15, 20g creatine, 10g L glutamine, Urolithin A, NR, R-ALA 32oz room temp water + LMNT 30min walk 3mg Zyn pouch (nicotine), 20g exogenous ketones, 0.2g psilocybin mushroom microdose. Crank out 2 hours hyper productive work and substantial uplift in mood (the mood part I largely credit to improvements in gut health, oral BPC/KPV and glutamine playing a role here) and the microdose of psilocybin.

I know this is probably super boring compared to the amazing things Anthony brings to the table. But I’m truly looking for amazing quality olive oil and I’m getting analysis paralysis with the marketing and hype. Does anyone have insight or even better, experience with sourcing some high quality polyphenol rich olive oil? Thank you for any info

I’m testing out something new and wanted to bring you all along for the ride. I’ve started a daily learning experiment where I study new material each morning and then teach it back here to lock it in and spark better conversations inside the community. The goal is twofold: it helps me deepen my own understanding and gives all of us a chance to explore new ideas together. Some of what I’ll be diving into might sound a little weird at first it’s on the edge of where cellular medicine, physics, and performance meet but that’s exactly why I want to share it here. This is me getting my reps in, learning how to explain complex ideas simply so I can keep improving the way I teach and support everyone who trusts me with their health. Skool is officially in session and this is Day One. Coherence is one of those concepts that sounds abstract until you feel it. Every living system, from a single cell to a full human being, depends on rhythm and timing. When that rhythm is in sync, energy flows efficiently, signals are clear, and the system performs at its best. In biology, this rhythm is called coherence. Inside your cells, coherence is the difference between energy being stored as ATP or lost as heat and inflammation. Each mitochondrion operates like a small power plant. Its inner membrane holds a separation of charge about minus one hundred eighty millivolts that acts like the height difference of water behind a dam. This energy difference is the reason mitochondria can turn food and oxygen into usable fuel. Protons are pumped to one side of the membrane, building pressure, and when they flow back through the turbine-like ATP synthase, energy is released in a controlled, efficient way. If the membrane potential weakens, it’s like the dam lowering; water spills over without spinning the turbines, and you feel it as fatigue or slower recovery. In training terms, imagine the smooth rhythm of a strong set of squats. At the start, your body and breath are synchronized. Energy moves cleanly, the movement feels effortless, and power output is high. As fatigue builds, you lose that rhythm. The burn you feel in your muscles is the result of protons accumulating faster than they can be cleared. The gradient across your mitochondrial membranes collapses, energy flow becomes noisy, and contraction efficiency drops. That sensation is coherence breaking down in real time.