Just curious, other than looking for changes in the mirror, are there any other indicators that would tell me it’s working? I only ask because on SLU I felt a noticeable difference in my endurance during cardio sessions… On Tirz, my appetite tanks… Beta Alanine makes the fingers tingle.. Know what I’m sayin? A

What is Anthony’s opinion on allulose? I know he recommends trehalose, which I’ve also been using lately. However, I’ve been reading a lot of positive things about allulose and its effects on metabolic pathways in the body. What is the difference in their effects in this context? I’m not referring to carbohydrate content, calories, or sweetness, but rather their impact on fat metabolism, glycogen storage, inflammatory processes, and autophagy etc

@Anthony Castore what are your thoughts of TND1128 being superior over NMN as a NAD+ precursor? The studies I’ve read indicate that TND1128 is a superior MAM+ precursor for activating SIRTUINS, help self regulate redox, with anti antioxidant and anti-inflammatory properties. That being said, all the studies were conducted on mice and we know that there’s not a direct correlation.

Any thoughts on efficacy and safety for FLGR 242 and Klotho ? I’ve listened to many in the field that rave about FLGR 242 and knowing that you are dialed in and can understand the science and research I thought I would reach out and ask you . What I do 7 understand in a limited way is a binding mechanism using albumin that apparently reduces some serious side effects that people experience with Follistatin 344. The protocol I have been on has been amazing for fat loss ….started at 195 and down to 176 and mostly fat loss but now my goal is some more muscle . I am doing a full panel next week for hormone level and thyroid etc which will help me take next steps . Thanks in advance . P.S….numerous people here in my circle are asking how I’m doing this and I just direct them by invite to your site . I’m extremely grateful and wish you were here in Canada 😜

Hi Anthony, I recently saw this rodent study done by Ben Bikman's lab on BHB and 1,3 BD. https://www.mdpi.com/2072-6643/18/4/675 This study found: "1,3 BD induces significant hepatic stress characterized by ATP depletion, oxidative stress, and lipid accumulation. These results align with and extend recent findings by Ari and D’Agostino demonstrating formulation-dependent hepatic outcomes of chronic ketone supplementation, where ketone salts preserved liver health while BD-based ketone esters and precursors drove inflammation and steatosis" What are your thoughts on their findings? Does their study design bias the outcome? Are there similar studies that show that 1,3 BD is neutral in its effects? Does KineticPro or KE4 use ketones that are different than what was studied here? (It looks the same to my naive and uninformed eyes, so that's why I'm asking.)