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The Next Generation in Metabolic Optimization: Bioglutide (aIQ-931)
At AlchemIQ Labs, we don’t just follow the science we help write it. While others speculate, we lead with rigorous research, innovative formulations, and uncompromising integrity. Our mission is simple but bold: to redefine what’s possible in cellular medicine and performance by delivering compounds that actually work, not just buzzwords. Every formula we create is grounded in peer-reviewed science. Biogoutide is a first-in-class oral therapy designed to go beyond standard GLP-1 drugs. Where current treatments often sacrifice muscle or cause harsh GI side effects, Bioglutide leverages a quadruple receptor agonist strategy, activating IGF-1, GLP-1, GIP, and glucagon receptors simultaneously. This synergy creates a powerful metabolic reset: GLP-1 + GIP → enhance insulin secretion, improve glucose control, and suppress appetite at the brain level. Glucagon receptor → boosts fat oxidation and raises energy expenditure. IGF-1 receptor → protects and preserves lean muscle mass while fat is being mobilized. Unlike injectables, Bioglutide is orally bioavailable, and is being researched as a once-daily, and able to cross the blood–brain barrier for central appetite modulation. Clinical Proof In Phase 2 clinical trials (13 weeks, 125 participants): Up to 13.8% body weight reduction at the top dose (150 mg/day).No muscle loss observed a key differentiator from GLP-1 monotherapies. Mild side effects only (nausea, diarrhea in <8%), with no severe adverse events. These results position Bioglutide as a superior alternative to single-pathway GLP-1 drugs like semaglutide and tirzepatide, especially for those prioritizing fat loss without compromising muscle integrity. Why It Matters Current GLP-1 agonists are effective but blunt tools—they drive appetite suppression and weight loss but often at the expense of lean tissue and overall metabolic resilience. Bioglutide changes the game by: Targeting multiple pathways at once for balanced, durable results. Preserving muscle through IGF-1 activation while accelerating fat oxidation.
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The Ketone Playbook: My Go-To Protocols + Live Q&A
🚀 Ketones = Game Changer. This is the thread where I’ll drop my go-to ketone protocols ⚡️ and YOU can fire away with any questions. 💬 Comment your experiences, hacks, and questions below—let’s build the ultimate ketone resource together. 👀 Webinar coming soon… stay tuned. Practical Dosing Blueprints 1.Pre-Workout Protocol (Performance & Focus) Goal: Elevate ketones, buffer acidosis, support hydration & glucose supply. - Hydration: 500–750ml water + electrolytes (sodium 500–1000mg, potassium 200–400mg). - Bicarbonate: 0.3 g/kg sodium bicarbonate (~20g for 70kg athlete), dissolved in water. Take 90–120 min before session to minimize GI upset. - Trehalose (Carbohydrate): 15–25g as slow-release carb for sustained glycogen supply. - Ketone Ester (D-BHB/1,3-BD): 15–25ml (~7–12g KE) 10–15 min pre-warmup. Effect: Dual-fuel system (glucose + BHB), reduced acidosis, enhanced mental focus . 2.Intra-Workout Endurance Protocol Goal: Sustain metabolic efficiency, prevent bonk, extend time-to-exhaustion. - Every 60 min: Trehalose or isomaltulose: 20–30g (slow carb). Ketone Ester: 10–15ml (~5–7g KE). - Optional: electrolyte top-up (sodium/potassium). Effect: Preserves glycogen, stabilizes glucose, sustains BHB 1–3 mM . 3.Post-Workout Recovery Protocol Goal: Accelerate glycogen resynthesis, repair, and inflammation control. - Protein: 20–30g whey or EAAs. - Carbs: 40–60g high-GI glucose or maltodextrin. - Ketone Ester: 20–30ml (~10–15g KE), taken 30–45 min post-exercise (separate from carb/protein drink for maximal signaling). - Trehalose: Add 10–15g if training volume is very high or glycogen depleted. Effect: 50% faster glycogen replenishment, stronger mTOR activation, reduced inflammation . 4.Sleep Recovery Protocol (Athletes) Goal: Deep recovery, improve next-day performance. - Ketone Ester: 2.5–10ml (~1–5g KE) immediately before bed. - Optional: Magnesium glycinate/threonate for additional relaxation.
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Updates: SLU webinar slides and Protocol Breakdown
I hope everyone had a fantastic weekend! We’ve got some exciting updates this week, and I wanted to bring everything together in one post for simplicity. First, big news the Kenetik Pro Buyers Club is officially launching! If you’ve been curious about trying the supplement I personally rely on the most, ketone esters, now’s your chance. I’m thrilled to be able to offer both access and savings. I’ve put together a thread that breaks down everything you’ll need—how to order, how many bottles you’ll likely go through in a month, and pricing details. Next, a quick clarification on the upcoming free webinar. This one is going to pull back the curtain on my own protocol and thought process. You’ll get the full, no-holds-barred breakdown of what I take, why I take it, and how I pair it with training, nutrition, and lifestyle strategies. My goal is to help you see things through a systemic lens so you can craft protocols that are more precise and effective. I want this to be fun, transparent, and useful and I’ll say up front, I’m learning every day right alongside you. Feedback (positive or critical) is always welcome. My plan is to make this a monthly feature, including not just my own protocols but also other people’s, so we can grow as a community of protocol designers together. Finally, a huge thank-you to Kassem Hanson of N1. He’s been an incredible resource for me personally and for our community. I’m currently enrolled in his program design mentorship, and if you want to learn the N1 approach, I can’t recommend their online and in-person seminars enough. They teach customization and critical thinking in a way that resonates whether you’re brand-new or decades into this field. Kassem generously edited the SLU webinar from Saturday, and I’ll be posting the recording soon for anyone who couldn’t attend. I’ll also be sharing the slides here, so if you haven’t received them by email, keep an eye out for the link. Link to webinar reply Thank you all so much for your support and for the energy you bring to this community. Everything we’re building here is possible because of each of you. Please don’t hesitate to reach out if there’s something you’d like to see more of, or if you have suggestions on how I can serve you better. I’m here for you guys!
Updates: SLU webinar slides and Protocol Breakdown
New question on exogenous ketones for Anthony and others
I just listened to a recent podcast with Dr. Dom D’Agostino, whom I’ve been following for almost two decades and whose opinion I highly value. If I understood correctly, he doesn’t seem particularly enthusiastic about ketone esters. (I know this may be related to the promotion of ketone salts, but he is probably the most important ketone researcher at the moment.) His reasons: a) The rapid and excessive rise in ketones triggers an insulin response, which in the context of fasting and a ketogenic diet is not ideal. I assume it may make sense post-workout, when glycogen stores are being replenished. In addition, this insulin release suppresses endogenous ketone production. b) The second reason seems more concerning. Ketone esters are said to be metabolized by the liver in a way similar to alcohol, and if used too frequently or long-term, they could place a heavy burden on the liver—especially in older individuals or those on multiple medications. He also mentioned a new triester, without the alcohol part, as a potentially better next-generation option. Overall, he seems to favor a combination of MCTs and ketone salts, which both boost endogenous ketone production and provide some exogenous ketones. The electrolytes included are not a problem ( within a ketogenic diet—in fact, they are beneficial) .
Osteopenia Treatment Options – Any Role for Peptides?
I have a client diagnosed with osteopenia who would like to address the problem. The client is woman middle-aged. In addition to dietary changes, sufficient protein intake, weight-bearing exercise, and supplementation with Vitamin D3 + K2 + calcium, are there also any peptides that could be useful?
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Castore: Built to Adapt
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Where science meets results. Learn peptides, training, recovery & more. No ego, no fluff—just smarter bodies, better minds, built to adapt.
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