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Statement from Anthony Castore and AlchemIQ on the Bioglutide / Biomed Situation
Every industry has defining moments the ones that separate hype from principle and reveal who’s truly here for the long game. This is one of those moments for ours, and I want to be completely transparent about where we stand. Biomed Industries is the company credited with discovering Bioglutide (NA-931) and developing it as a next-generation GLP-based compound. Our raw materials came from the same supplier Biomed reportedly uses. Recently, serious accusations have surfaced against Biomed claims of fraudulent data, lack of publicly verifiable sequence information, and the absence of a disclosed CAS number or molecular structure. The accuser has raised valid scientific concerns that deserve to be addressed. At the same time, these allegations are new, and Biomed has not yet had the opportunity to publicly respond. That’s why we are pausing not panicking. Even in moments like this, our safeguards remain strong. We can fully document purity through HPLC and LC-MS, confirm sterility and endotoxin levels, and provide verified Certificates of Analysis. However, without a public reference structure or sequence, no lab including ours can confirm 100% molecular identity. We can verify that a compound is clean, sterile, and potent, but we can’t compare it to a molecule that’s never been fully published. To give some context, CB4211 is a great example of how innovation often moves faster than public documentation. This compound, developed for mitochondrial health and metabolic optimization, has been prescribed by physicians and compounded by pharmacies despite its structure, sequence, and CAS never being publicly released. That doesn’t make it ineffective or illegitimate it simply illustrates that, just like Bioglutide, the available data can only go so far. In both cases, these products are sourced, tested, and manufactured to the highest standards, with thorough purity and safety testing but without full structural transparency. That means identity and uniqueness are established through trust, testing, and outcomes rather than public disclosure. For all we know, CB4211 could be a more advanced form or reformulated analog of MOTS-c—or perhaps just a more expensive version under a new label. Until formal sequencing or patent releases are made public, no one can say for sure. This doesn’t discredit its value; it simply reminds us that in early-stage biotech, certainty often trails behind discovery. That’s why rigorous testing, ethical sourcing, and open communication about what is known and what isn’t are so vital.
Is Anyone Here Personalizing Their Lifestyle Nutrition Peptide Supplement Protocols Based on Their DNA?
Has anyone here actually paired their peptide or supplement protocols with their genetic profile? I see a ton of conversations about peptides, supplements, fasting, lifestyle stacks, etc, but way fewer people talk about whether any of that lines up with their actual genome. We all respond differently at the cellular level, and it makes me wonder how many people are running protocols that help them… or maybe even work against their biology. Has anyone used any of the deeper DNA services to map out things like: • mitochondrial efficiency • inflammation pathways • methylation function • detox / redox capacity • growth factor signaling • longevity-related SNPs (FOXO3, SOD2, APOE, MTHFR, etc.) • recovery and injury-related genes (COL1A1, VEGF, ACTN3, etc.) I’m asking because I recently pulled my own gene set and I’m trying to understand how to match it with: • peptide choices (GH secretagogues, mitochondrial peptides, repair peptides, etc.) • supplements (AKG, PC, ALA, NAD+, polyphenols, etc.) • lifestyle (fasting windows, training style, sleep strategies) • nutrition (carb tolerance, fat metabolism, inflammation triggers) Basically, shouldn’t our protocols be customized rather than copy-and-paste? What works amazing for one person might be useless for someone whose FOXO3 is upgraded, or whose SOD2 or MTHFR pathways struggle, or who has variations affecting GH/IGF-1 signaling. Here’s my own list of gene variants if anyone here has insight or has gone down this rabbit hole. I’d love to hear from anyone who’s mapped peptides or supplements to their genome in a structured way.
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Nicotine
Hello, I hope everyone is enjoying there thanksgiving today. I was curious to see what everyone thought about nicotine? I have used it in some of the troscription products and enjoyed the mental and sometime physical lift that gives me. (It is combined with methylene blue, caffiene and CBD in in that preperation however.) The more research i do on it, the more i realize what a bad wrap it has gotten, and what benefits it actuall offers to the user. Anyway, would love to hear people thoughts on the topic, and what dosage you use if you use it? Thanks
Big increase in RHR
June - August 2024 I was living in Portugal, lovely sun in the morning. Morning steps, cold plunge and sauna everyday. Super cool room on a night. I was on TRT and GH and RHR got down to about 48bpm. This year June 2025 I started reta, still on gh, trt......and I only went up to 3mg a week. My RHR has gone up to almost 70. Even when I stopped in for 4 weeks it didn't really move lower. Now I'm not sure why it's staying spiked, I was considering adding in a low dose Nebivolol but I know I shouldn't need to take something just to counteract that. We all know RETA increases RHR in a lot. But what else can I look at to see if anything else is causing this? Thanks
peptide source
I’m wondering where everyone gets their injectible peptides from? Anthony, does SSRP have a preferred source that us in the community could purchase from? Any online clinic where a virtual consult could be done and the peptides prescribed from a compounding pharmacy and shipped to our residence? I have a functional medicine doctor in miami but he requires you pick them up and they are already reconstituted which affects their expiration.
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