Mar 25 • Peptides
Evidenced Gym Recovery Protocol: Holistic Optimisation for Training Performance, Muscle Repair, and Long-Term Resilience
This is designed to manage local and systemic fatigue.
I will assume that HRV, sleep and stress management, nutrition and hydration, and baseline supplementation are covered.
There's quite a lot to cover, but I will start with the most common
The Wolverine Stack (BPC-157 + TB-500) – Core for Muscle/Tendon Recovery
Mechanism & Evidence: BPC-157 (gastric-derived) promotes angiogenesis, tendon-to-bone healing, and anti-inflammation (strong rat/muscle studies). TB-500 (thymosin beta-4 fragment) drives cell migration, reduces fibrosis/scarring. Synergistic "Wolverine" effect accelerates systemic repair and DOMS clearance—ideal for heavy lifters, preventing overuse issues. Preclinical synergistic effect confirmed; human data anecdotal/small pilots show faster musculoskeletal recovery.
Precise Dosages (Research Protocols):
- BPC-157: 250–500 mcg daily (subQ, anywhere). For intense training phases: split AM/PM or localise near worked muscles. Run 4–8 weeks.
- TB-500: 2–5 mg weekly (or 2.5 mg twice/week) subQ. Longer half-life allows less frequent dosing.
- Training-Specific Adaptation: Use systemically for damage prevention; expect reduced soreness and quicker strength rebound. Cycle 6–8 weeks, then maintenance or off.
Safe Administration & Warnings:
- Do NOT mix in the same vial (different pH/stability → degradation risk). Reconstitute separately with bacteriostatic water (BAC). Draw into separate syringes
- Reconstitution/Storage (standard sterile protocol): 5 mg vial: Add 0.5–2 mL BAC water (e.g., 2 mL = 250 mcg/0.1 mL for easy dosing). Swirl gently (do not shake). Refrigerate (stable 4–6 weeks post-reconstitution) usually longer. Store powder frozen/dry long-term. Use alcohol swabs; insulin syringes (U-100).
Mitochondrial Optimisation: MOTS-c + SS-31
Heavy training depletes ATP; these "exercise mimetics" restore energy factories.
Dosages for Gym Recovery:
- MOTS-c: 5–15 mg/week (split 3x, e.g., M/W/F; 30 min pre-workout subQ). Improves metabolism, endurance, and fat oxidation (mouse/human exercise studies).
- SS-31 Sequencing Debate (two evidence-based schools):
- Repair-First (SS-31 4 weeks prior): For older/fatigued athletes with mitochondrial damage—fixes cardiolipin/electron leaks first (aged-muscle studies show restored exercise tolerance). Then add MOTS-c.
- Preventative (MOTS-c first): For healthy trainees—builds new mitochondria via biogenesis/mitophagy; SS-31 optional later for stabilisation.
- Recommendation: Start MOTS-c if under 40/healthy; SS-31 lead-in if burnout history. Stack synergistically long-term.
Growth Hormone Secretagogues (CJC-1295 no Dac/Ipamorelin or Tesamorelin)
Benefits for Recovery: Amplify nocturnal GH/IGF-1 pulses → deeper sleep, muscle repair, fat mobilisation, collagen synthesis. Synergistic with Wolverine for systemic recovery.
Options & Dosages:
- CJC-1295 + Ipamorelin (cost-effective; most common): 200–300 mcg each nightly, subQ, fasted, 30–60 min pre-bed. CJC without DAC (short pulse). Evidence: Human trials show sustained GH/IGF-1 elevations and improved sleep/recovery.
- Tesamorelin (visceral fat specialist; FDA-approved for that indication): 1–2 mg daily subQ (pre-bed). Higher receptor affinity adds cognitive/neuroprotective perks.
- Stack Synergy (Tesamorelin + Ipamorelin): "Fill reservoir + release" for massive natural GH pulse. Inject fasted pre-bed.
MK-677 + Cardarine Add-On (Oral Option for Metabolic/Recovery Support):
- MK-677 (Ibutamoren): 10–25 mg oral nightly. Boosts GH/IGF-1 24/7; improves sleep, appetite, lean mass (human studies). Recovery angle: faster repair via IGF-1. Watch lipids/glucose.
- Cardarine (GW-501516): 10–20 mg daily (morning). PPAR-delta agonist → endurance/fat oxidation (animal data: 50–70% endurance gains).
- Stacks with MK-677 for recomp without suppression/PCT.
- Evidence limited to preclinical; WADA-banned. Use 8–12 weeks; monitor bloods.
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Evidenced Gym Recovery Protocol: Holistic Optimisation for Training Performance, Muscle Repair, and Long-Term Resilience
skool.com/whwido
A science & experience-based 4-phase strength method that keeps you progressing long after other programmes stall. For any age or level, no upsells.
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