Activity
Mon
Wed
Fri
Sun
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
What is this?
Less
More

Memberships

Endless Evolution w/ Duffin

2.2k members • Free

Aegis Nutrition Academy

80 members • $29/m

Castore: Built to Adapt

310 members • Free

TPC ARMY

137 members • $200/m

Light Skool

798 members • Free

5 contributions to Castore: Built to Adapt
The Next Generation in Metabolic Optimization: Bioglutide (aIQ-931)
At AlchemIQ Labs, we don’t just follow the science we help write it. While others speculate, we lead with rigorous research, innovative formulations, and uncompromising integrity. Our mission is simple but bold: to redefine what’s possible in cellular medicine and performance by delivering compounds that actually work, not just buzzwords. Every formula we create is grounded in peer-reviewed science. Biogoutide is a first-in-class oral therapy designed to go beyond standard GLP-1 drugs. Where current treatments often sacrifice muscle or cause harsh GI side effects, Bioglutide leverages a quadruple receptor agonist strategy, activating IGF-1, GLP-1, GIP, and glucagon receptors simultaneously. This synergy creates a powerful metabolic reset: GLP-1 + GIP → enhance insulin secretion, improve glucose control, and suppress appetite at the brain level. Glucagon receptor → boosts fat oxidation and raises energy expenditure. IGF-1 receptor → protects and preserves lean muscle mass while fat is being mobilized. Unlike injectables, Bioglutide is orally bioavailable, and is being researched as a once-daily, and able to cross the blood–brain barrier for central appetite modulation. Clinical Proof In Phase 2 clinical trials (13 weeks, 125 participants): Up to 13.8% body weight reduction at the top dose (150 mg/day).No muscle loss observed a key differentiator from GLP-1 monotherapies. Mild side effects only (nausea, diarrhea in <8%), with no severe adverse events. These results position Bioglutide as a superior alternative to single-pathway GLP-1 drugs like semaglutide and tirzepatide, especially for those prioritizing fat loss without compromising muscle integrity. Why It Matters Current GLP-1 agonists are effective but blunt tools—they drive appetite suppression and weight loss but often at the expense of lean tissue and overall metabolic resilience. Bioglutide changes the game by: Targeting multiple pathways at once for balanced, durable results. Preserving muscle through IGF-1 activation while accelerating fat oxidation.
1 like • 12d
@Joshua Rigg interested to hear your ongoing experience, thanks for sharing
0 likes • 11h
@Anthony Castore Sema, Tirze, Reta all have different… I’m not sure if the correct term is “binding affinity” or “chemical action” but simply put Tirze acts on GLP1 more weakly than GIP, and more weakly on GLP1 than say Sema (if I understand correctly). Is NA-931 considered “strong” on IGF?
MOTS-c + SS-31 protocol – does this combination make sense
I got a few vials of MOTS-c and SS-31, and if I understand correctly, this seems like an interesting complementary combination for improving mitochondrial function. MOTS-c activates AMPK, while SS-31 targets cardiolipin and works as an antioxidant. Here’s what I was thinking: MOTS-c: subcutaneous, 5 mg, 2x per week, for 4 weeks SS-31: subcutaneous, 2 mg daily, 3x per week, mainly on rest days Does this protocol make sense, and what kind of supplements could I add alongside to maximize the benefits of the cycle?
3 likes • 8d
I love MOTS on training SS on rest days, I think you’ll enjoy this protocol
Increasing SLU dose…bolus or split?
I’ve been running 250mcg SLU-PP-332 fasted AM 5x weekly. Taken with NR, Urolithin A, Fatty15. I’m going to be increasing my dose to 500mcg and curious if people are having more success going with a bolus dose and taking the full 500mcg AM, or splitting it 250 AM and 250 afternoon?
0 likes • 12d
@Drew Wurst get some DHT Enanthate for that purpose Primarily for fat loss downstream of mitochondrial biogenesis but I do find I get a couple extra reps out of it in a hypertrophy training context
1 like • 12d
@Drew Wurst none taken, fwiw at low doses it’s not suppressive, actually boosts natural test production. Has the potential to obviate TRT for those with secondary hypogonadism (the vast majority on TRT today)
@everyone what is your preferred method of maintaining optimal testosterone levels?
I would love to hear everyone’s thoughts on preferred method of TRT(exogenous injectable route, or oral route). I am currently on testosterone enthanate 300 a week and primobolan enthanate. I have also tried jatenzo (oral testosterone). I have had great results with that where my free test was higher and total was lower. Also are there any natural ways(supplements, nutrition, and sleep). What peptides help with upping testosterone, and balancing estrogen? I would love to hear all of your opinions and learn something new that I may have missed.
0 likes • 19d
@Drew Wurst I’m a patient care coordinator @ an online telehealth clinic… I read labs, talk to patients, and design their protocols for a living (including HRT). Many reach us after making all the lifestyle adjustments with marginal success, they THRIVE on HRT. The ones that get to us early, don’t have the foundations laid? Marginal benefit, they also tend to be the ones asking about dose increases or additional compounds, go figure
0 likes • 19d
Test C or E daily if willing, 3x weekly, or 2x weekly at absolute minimum. Most guys on TRT are secondary, they could improve their levels naturally (the deck is stacked against us in the modern environment) but most aren’t willing to make the significant lifestyle changes necessary Peptides I don’t see doing much for T levels (would be happy to be proven wrong here), I’m newer to bioregulators but am hopeful testoluten could be a needle mover for some men
Allergic reactions to MOTS-C?
I’m hearing reports of people going into anaphylactic shock from MOTS-C administration. I will be utilizing it for the first time in the upcoming week at a planned dose of 5mg 2x weekly. Any insight on these alleged reactions to the injections? Precautions to take? SubQ vs IM administration?
0 likes • 21d
Could be wrong but I think this is from the days when people thought it degraded immediately after reconstitution so they were injecting the entire vial
1-5 of 5
Brandon Brassard
2
15points to level up
@brandon-brassard-3064
Coach working with lifestyle, anti-aging, and woman’s health clients

Active 1h ago
Joined Aug 29, 2025
Powered by