Cellular Level: What Happens Inside the Cells
Healthy brain and gut cells need stable mitochondrial energy (ATP).
Peanut butters made with industrial oils (like hydrogenated soybean or cottonseed oil) are high in omega-6 linoleic acid (LA), which -
- Disrupts mitochondrial membranes and electron flow.
- Increases oxidative stress (more free radicals, less energy).
- Impairs fatty acid oxidation, lowering the cell’s energy output.
- This mean your cells literally have less energy. Almost all diseases can be directly connected to poor mitochondrial function, including cancers.
For someone with anxiety or depression, this means-
- Less ATP leading to slower brain metabolism
- More oxidative stress leading to cellular inflammation
- Reduced neurotransmitter balance leading to higher risk of anxiety, irritability, and mood dips
Inflammation & Neurotransmitter Imbalance
Chronic gut and cell inflammation increase the enzyme IDO (indoleamine 2,3-dioxygenase), which diverts tryptophan away from serotonin production and toward kynurenine, a neurotoxic compound.
That Simply means-
- Less serotonin leading to more anxiety and low mood
- More kynurenine leading to more brain inflammation and “brain fog”.
- We'll talk more about this in Part 3
So even a small daily serving of processed peanut butter could worsen mood symptoms over time if it increases inflammation or gut irritation.
A Better Alternative
Just choose-
- 100% nuts only (no added oils or sugar)
- Stored in glass, not plastic (to avoid BPA/BPS exposure)
- Refrigerated after opening (to prevent rancidity and mold)
- add your own sea salt if desired.
Better nut butters, Almond, Cashew, Pistachio, Macadamia
- Raw almond butter (lower omega-6 load)
- Macadamia or cashew butter (more monounsaturated fats, gentle on gut)
- Coconut butter (mood-stabilizing fats like lauric acid)
What's your favorite nut butter or substitute?