🚀 Ketones = Game Changer. This is the thread where I’ll drop my go-to ketone protocols ⚡️ and YOU can fire away with any questions. 💬 Comment your experiences, hacks, and questions below—let’s build the ultimate ketone resource together. 👀 Webinar coming soon… stay tuned. Practical Dosing Blueprints 1.Pre-Workout Protocol (Performance & Focus) Goal: Elevate ketones, buffer acidosis, support hydration & glucose supply. - Hydration: 500–750ml water + electrolytes (sodium 500–1000mg, potassium 200–400mg). - Bicarbonate: 0.3 g/kg sodium bicarbonate (~20g for 70kg athlete), dissolved in water. Take 90–120 min before session to minimize GI upset. - Trehalose (Carbohydrate): 15–25g as slow-release carb for sustained glycogen supply. - Ketone Ester (D-BHB/1,3-BD): 15–25ml (~7–12g KE) 10–15 min pre-warmup. Effect: Dual-fuel system (glucose + BHB), reduced acidosis, enhanced mental focus . 2.Intra-Workout Endurance Protocol Goal: Sustain metabolic efficiency, prevent bonk, extend time-to-exhaustion. - Every 60 min: Trehalose or isomaltulose: 20–30g (slow carb). Ketone Ester: 10–15ml (~5–7g KE). - Optional: electrolyte top-up (sodium/potassium). Effect: Preserves glycogen, stabilizes glucose, sustains BHB 1–3 mM . 3.Post-Workout Recovery Protocol Goal: Accelerate glycogen resynthesis, repair, and inflammation control. - Protein: 20–30g whey or EAAs. - Carbs: 40–60g high-GI glucose or maltodextrin. - Ketone Ester: 20–30ml (~10–15g KE), taken 30–45 min post-exercise (separate from carb/protein drink for maximal signaling). - Trehalose: Add 10–15g if training volume is very high or glycogen depleted. Effect: 50% faster glycogen replenishment, stronger mTOR activation, reduced inflammation . 4.Sleep Recovery Protocol (Athletes) Goal: Deep recovery, improve next-day performance. - Ketone Ester: 2.5–10ml (~1–5g KE) immediately before bed. - Optional: Magnesium glycinate/threonate for additional relaxation.

Question for those of you who buy peptides in bulk. How do you store your lyophilized (not reconstituted) peptides for the long-term? Thanks in advance!

One of the least appreciated but most critical aspects of long COVID is endothelial dysfunction. The endothelium lines every blood vessel, acting as a dynamic interface between blood and tissue. In healthy states, it regulates vascular tone, prevents clot formation, and coordinates nutrient delivery. In long haulers, endothelial cells remain injured and inflamed, leading to microclot formation, impaired oxygen delivery, and disrupted autonomic signaling. This explains why so many symptoms—from shortness of breath to brain fog to rapid heart rate—can be traced back to vascular chaos. Microclots are a defining feature. These are not the large clots that cause strokes or pulmonary emboli but tiny fibrin-rich clots resistant to normal breakdown. They trap proteins, inflammatory molecules, and even spike fragments, acting as persistent irritants in the circulation. By blocking capillary beds, they reduce oxygen delivery to tissues, creating hypoxia at the cellular level. This is one reason why long haulers feel exhausted after the smallest activity the oxygen never fully reaches their mitochondria. It is like trying to water a field with hoses full of pebbles: the flow trickles instead of streaming. Nitric oxide signaling is another casualty. Endothelial nitric oxide synthase normally produces NO to dilate vessels, improve blood flow, and support mitochondrial function. Oxidative stress, arginine depletion, and enzyme uncoupling reduce NO production in long COVID. Without it, vessels remain constricted, blood flow is irregular, and energy metabolism suffers. VEGF, the growth factor that directs vascular repair and new vessel formation, also becomes dysregulated, either underactive in some tissues or overactive in others, producing fragile and leaky capillaries. Together, this creates a vascular network full of potholes and detours instead of smooth highways. Autonomic dysfunction sits on top of this vascular instability. The autonomic nervous system depends on precise baroreceptor feedback from blood vessels to regulate heart rate and blood pressure. When endothelium and fascia baroreceptors are injured, the signals become erratic. The vagus nerve often loses tone, while sympathetic activity ramps up. The result is postural orthostatic tachycardia syndrome, dizziness, palpitations, and poor heart rate variability. Many long haulers describe it as their body “forgetting how to regulate itself.” In truth, the sensors and wiring have been damaged by inflammation and microclots.

Anyone have a dose range for this compound?

Where would you place Trehalose in a peri workout setting? Versus HBCD which is commonly used intra workout.