Why 5-Amino-1MQ Should Be the LAST Thing You Add to Your Cut 🔬
If you're thinking about adding 5-Amino-1MQ to your fat loss phase, pump the brakes. Here's why it should be the absolute last thing on your supplement list—not the first. The Harsh Truth About 5-Amino-1MQ: It's NOT a beginner fat loss tool. It's a specialized compound for a very specific situation: prolonged caloric deficits where your metabolism has adapted and fat loss has stalled. What Is 5-Amino-1MQ? 5-Amino-1MQ is a small molecule that inhibits the enzyme NNMT (nicotinamide N-methyltransferase). When NNMT is blocked, it increases NAD+ levels in cells, which can enhance metabolic rate and fat oxidation. Sounds amazing, right? Here's the catch... Why It ONLY Works in Prolonged Deficits: 1. It Addresses Metabolic Adaptation, Not Fat Loss Itself When you're in a caloric deficit for weeks or months, your body adapts by: - Downregulating thyroid hormones (T3/T4) - Reducing NEAT (non-exercise activity thermogenesis) - Decreasing overall metabolic rate - Increasing hunger hormones 5-Amino-1MQ helps combat THIS adaptation—it doesn't directly cause fat loss. It helps keep your metabolism from cratering during extended cuts. 2. Your Metabolism Isn't Adapted Yet (Early in a Cut) If you're 2-4 weeks into a cut and fat is still coming off easily: - Your metabolism is still running normally - Your thyroid is functioning well - You don't have a significant metabolic adaptation yet Adding 5-Amino at this point is like putting premium gas in a Honda Civic—unnecessary and a waste of money. 3. The Basics Are What Matter First Before even THINKING about 5-Amino-1MQ, you should have these dialed in: - Consistent caloric deficit (tracked accurately) - High protein intake (1g per lb bodyweight minimum) - Regular training program - Adequate sleep (7-9 hours) - Step count/NEAT management - Stress management If ANY of these aren't optimized, 5-Amino won't save you. When Should You Actually Consider 5-Amino-1MQ? ONLY when you've hit these criteria: