💊 The Science Behind Topical AHK-Cu for Hair Regrowth
A lot of you have been asking about AHK-Cu (Copper Peptide) for hair loss, so let's dive deep into the mechanisms and why this compound is getting so much attention in the hair restoration space.
What is AHK-Cu?
AHK-Cu is a synthetic copper peptide (copper tripeptide-1) that's been extensively studied for wound healing and tissue regeneration. The "Cu" refers to the copper ion that's bound to the peptide sequence, which is critical for its biological activity.
Mechanisms of Action for Hair Regrowth
1. DHT Inhibition
AHK-Cu has been shown to inhibit 5-alpha reductase, the enzyme that converts testosterone into DHT (dihydrotestosterone). DHT is the primary hormone responsible for androgenic alopecia (male/female pattern baldness). By blocking this conversion at the scalp level, you're addressing one of the root causes.
2. Follicle Stem Cell Stimulation
Copper peptides stimulate hair follicle stem cells and promote the transition from telogen (resting phase) to anagen (growth phase). This means dormant follicles can potentially be reactivated and existing growth cycles can be extended.
3. Increased Blood Flow & Angiogenesis
The copper component promotes angiogenesis (formation of new blood vessels) in the scalp, which improves nutrient and oxygen delivery to hair follicles. Better blood flow = healthier follicles = better growth.
4. Collagen & Elastin Production
AHK-Cu stimulates collagen and elastin synthesis, which strengthens the dermal papilla and extracellular matrix surrounding hair follicles. This creates a more supportive environment for robust hair growth.
5. Anti-Inflammatory Effects
Chronic inflammation is a lesser-known contributor to hair loss. Copper peptides have anti-inflammatory properties that can reduce scalp inflammation and create a healthier environment for follicles to thrive.
6. Antioxidant Activity
By scavenging free radicals and reducing oxidative stress in the scalp, AHK-Cu helps protect follicle cells from damage that can lead to premature hair loss.
Why Topical Application?
Topical application allows for:
  • Direct targeting of the scalp and follicles
  • Higher local concentrations without systemic exposure
  • Minimal side effects compared to oral DHT blockers
  • Synergy with other topicals like minoxidil or tretinoin
Typical Protocol
Most research suggests applying 0.5-2mg of AHK-Cu per application, typically mixed into a carrier solution (like minoxidil, dermaroller serum, or even a simple water/propylene glycol mix). Application 1-2x daily to affected areas.
🎉 Ion Peptide NOW HAS AHK-Cu IN STOCK!
I know many of you have been waiting for this. Ion Peptide is currently stocking AHK-Cu 100mg vials, and they're running a limited-time promotion.
Use code derek for 20% off right now:
This is one of the most requested peptides I've been asked about, and it's great to finally have a reliable source with fresh COAs. If you've been on the fence about trying a topical protocol for hair regrowth, this is a solid option to explore.
Questions? Drop them below. Let's discuss protocols, stacking options, and real-world results. 💬
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Derek Pruski
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💊 The Science Behind Topical AHK-Cu for Hair Regrowth
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