The downsides of synthetic GH and transition to Peptides

Over the past few years, I’ve been using GH fairly regularly. I have access to high-quality pharmaceutical-grade GH, so I didn’t overthink it. At my age (54), the difference in how I feel, recover, and sleep is definitely noticeable. That’s always been the main reason I’ve used it, and 2 - 3 IU per day was enough for me. I only increased the dose before a competition to enhance fat burning.

However, after listening to and reading content from Antony and Dr. Seeds, I came to understand that constant activation of mTOR and supraphysiological levels of IGF might improve well-being and appearance as we age — but they can also accelerate aging.

That said, I used GH mostly while on a ketogenic diet, where GH doesn’t significantly elevate IGF, so that likely minimized the effect.

Now I’ve been off GH for two months, and I’d like to test a protocol using GHRH and GHRP, aiming for more pulsatile GH release, and therefore potentially fewer negative effects on long-term health.

I have access to the following peptides:

Ipamorelin

Sermorelin

Fragment 176–191

IGF-1 DES

MK-677

PEG-MGF

MOD-GRF 1-29

CJC-1295 + DAC

IGF-1 LR3

What would be the best combinations for:

1. Long-term health