Please Help! Calling all you big brains. . .

Hi everyone. I need your help. I've got a client that I can't figure out. She's a 52 yo female who has been dealing with persistent (but slow) weight gain as well as so far unexplained puffiness/edema in her collarbone/clavicle area (looks like fluid filled pockets you can see and feel). Blood chemistry shows good glucose metabolism (verified by CGM, FI, FG, c-peptide, and hba1c - all optimal) but high BUN (27), CK (231), ALT (33), ApoB (112), and suboptimal HDL (particle size/number). Homocysteine, hs-CRP, thyroid (including antibodies), vitamin D, B12, etc. look good. Hormones are low except for testosterone which she was supplementing before we started working together - I've encouraged her to talk to a hormone specialist about balancing that better (including E2).

WBCs are up, but not alarmingly so. A GI Map showed almost everything <dl except opportunistic bacteria Staphylococcus aureus 9.59e2 High ↑ < 5.00e2 Streptococcus spp. 8.68e3 High ↑ < 1.00e3, and h.pylori 9 at 1.79x normal limit - doing PyloriX for that). Her Secretory IgA is also very low which makes me think she's been dealing with a chronically leaky gut and exhausted defense system.

Seems to me like she's got low-mid grade bacterial overgrowth but I feel like I'm missig something. We started with the Cell Core jumpstart/foundation kit and she started to see her reduced puffiness. It came back after she finished that initial kit. I'm trying to wrap my head around the total picture and develop a more thoughtful approach. Thinking continue with Cell Core, perhaps adding a Biocidin or antimicrobial to the mix.

Talk to me.

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