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Castore: Built to Adapt

310 members • Free

Endless Evolution w/ Duffin

2.2k members • Free

8 contributions to Castore: Built to Adapt
Question- heavy metal detox
I have a client whose HTMA shows a slow oxidizer pattern with low sodium, potassium, magnesium, zinc, and copper, alongside signs of adrenal/thyroid stress and some heavy metal presence (aluminum, mercury, arsenic). We’re focusing the first 90 days on mineral repletion, adrenal/thyroid support, and stabilizing the system before moving into deeper detox work. For those of you experienced in heavy metal detox, what additional strategies (nutraceutical, lifestyle, or peptide-based) have you found helpful in supporting safe and effective detox once mineral status is restored? In particular, I’d love to hear thoughts on peptides that may assist with binding, mobilizing, or mitigating the effects of heavy metals.
0 likes • 7d
@L S thank you!
1 like • 7d
@Anthony Castore this is amazing. Thank you!
Renal System | CKD
Something that i don't see addressed much along the longevity / biohacking / bodybuilding landscape is in-depth discussions, protocols, prevention or the chronic disease it's self - especially considering how important it is to daily life. @Anthony Castore Can you do a deep dive on this - addressing prevention, or peptides/bio regulators to protect the kidneys ?
0 likes • 22d
@Anthony Castore can’t wait!
Updates: SLU webinar slides and Protocol Breakdown
I hope everyone had a fantastic weekend! We’ve got some exciting updates this week, and I wanted to bring everything together in one post for simplicity. First, big news the Kenetik Pro Buyers Club is officially launching! If you’ve been curious about trying the supplement I personally rely on the most, ketone esters, now’s your chance. I’m thrilled to be able to offer both access and savings. I’ve put together a thread that breaks down everything you’ll need—how to order, how many bottles you’ll likely go through in a month, and pricing details. Next, a quick clarification on the upcoming free webinar. This one is going to pull back the curtain on my own protocol and thought process. You’ll get the full, no-holds-barred breakdown of what I take, why I take it, and how I pair it with training, nutrition, and lifestyle strategies. My goal is to help you see things through a systemic lens so you can craft protocols that are more precise and effective. I want this to be fun, transparent, and useful and I’ll say up front, I’m learning every day right alongside you. Feedback (positive or critical) is always welcome. My plan is to make this a monthly feature, including not just my own protocols but also other people’s, so we can grow as a community of protocol designers together. Finally, a huge thank-you to Kassem Hanson of N1. He’s been an incredible resource for me personally and for our community. I’m currently enrolled in his program design mentorship, and if you want to learn the N1 approach, I can’t recommend their online and in-person seminars enough. They teach customization and critical thinking in a way that resonates whether you’re brand-new or decades into this field. Kassem generously edited the SLU webinar from Saturday, and I’ll be posting the recording soon for anyone who couldn’t attend. I’ll also be sharing the slides here, so if you haven’t received them by email, keep an eye out for the link. Link to webinar reply Thank you all so much for your support and for the energy you bring to this community. Everything we’re building here is possible because of each of you. Please don’t hesitate to reach out if there’s something you’d like to see more of, or if you have suggestions on how I can serve you better. I’m here for you guys!
Updates: SLU webinar slides and Protocol Breakdown
1 like • Aug 27
Thank you!
🔥SLUPP332: The Fronteir of Mitochondrial Medicine 10AM EST🔥
Here’s a StoryBrand-style rewrite of your promo (clear problem → guide → plan → success → call to action): Most people who hear about new compounds like SLU-PP332 get stuck in two places: 1. The science feels too complicated. 2. The real-world application is missing. That’s frustrating, because you want to know if this tool can actually help you perform better, recover faster, and think clearer. Tomorrow morning at 10 a.m. Eastern, I’ll guide you through exactly what you need to know about SLU-PP332. You’ll get:• The backstory of where it came from and why it matters.• A simple explanation of how it works inside your cells.• Real-world dosing strategies you can actually use.• Objective and subjective ways to track if it’s working.• The key things you need in place to make it most effective. This isn’t about hype. It’s about clarity. When you understand both the science and the strategy, you stop guessing and start building momentum with confidence. Join us live tomorrow at 10 a.m. Eastern. The link is in the community calendar. Be part of the group that learns to use this breakthrough the right way while everyone else is still confused by the noise.
0 likes • Aug 23
@Anthony Castore can I get slides too please? [email protected]
Part 5 — The FGF21 Playbook
We’ve talked about what FGF21 is, when it rises, how it changes your mitochondria, and what science has shown us. Now let’s put it all together into something you can actually use. FGF21 isn’t a hormone you want blasting all the time. It works like a reset button short pulses of it help your mitochondria adapt and stay flexible. The key is to create the right contrast: some days that push it high, and other days that let it fall so your body stays sensitive. Here are the main levers you can pull: 1. Strategic sugar or carb surges. On training days, especially when you’re lifting hard or doing intervals, a surge of carbs with very low fat can spike FGF21. This is like revving your engine on purpose—it makes the mitochondria split into more units (fission) to keep up with demand. 2. Low-calorie or fasting days. On recovery or rest days, pulling calories back especially carbs and protein helps mitochondria repair (fusion) and recycle damaged parts (mitophagy). This is like parking the car in the shop so it can get tuned up. 3. Exercise. Whether it’s cardio, strength training, or even just a brisk walk, exercise is a universal trigger for FGF21. It’s like the master switch that makes sure your cells are ready to handle whatever fuel you throw at them. 4. Environmental stressors. Cold showers, sauna, or even just walking outside in the winter can bump up FGF21. These little stressors teach your mitochondria to stay resilient. 5. Support stack. Peptides like MOTS-c or SS-31, nutrients like CoQ10 and carnitine, and lifestyle choices like good sleep all improve how your body responds to FGF21. Think of these as the supporting cast that make the conductor’s job easier. Sample Weekly Calendar (200-lb man, 4 training days) Monday (Training – Fission Day)High carbs, low fat, lean protein. Example: fruit, juices, honey during the day; lean chicken and veggies at night. Tuesday (Rest – Fusion Day)Low calorie, higher fat, lots of vegetables. Example: salad with salmon and olive oil, roasted broccoli, eggs.
1 like • Aug 18
So good! Thank you @Anthony Castore .
1-8 of 8
Nicola Lewis
2
8points to level up
@nicola-lewis-1804
Functional health coach helping you heal from the inside out. Gut health, hormones, peptides & real food. Wellness is built, not bought.

Active 13h ago
Joined Aug 1, 2025
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