Diabetes and dementia are linked through a simple idea: the brain runs on energy, and diabetes disrupts the brain’s ability to use that energy. When the brain can’t make enough fuel, the neurons begin to slow their firing, mismanage inflammation, misfold proteins, lose membrane integrity, and eventually break down networks involved in memory, mood, coordination, and cognition. Dementia isn’t one event it’s a slow starvation paired with redox imbalance and membrane breakdown. Think of the brain like a city that runs on electricity. Glucose is the main power source. Insulin is the key that lets glucose into the cell. In diabetes especially Type 2 the key doesn’t work well. This creates “brain energy scarcity.” When neurons can’t pull glucose in effectively, they start producing large amounts of reactive oxygen species, shift into survival mode, and stop repairing themselves. Over time, this energetic bottleneck causes synapses to weaken, mitochondria to swell and fragment, and microglia to become overactive. This is why many experts call Alzheimer’s “Type 3 diabetes.” On a molecular level, poor glucose utilization collapses mitochondrial membrane potential, the voltage that drives ATP production. This voltage is the “life force” of the neuron. When it drops, the brain’s ability to manage calcium, recycle damaged proteins (autophagy), and maintain neurotransmitter balance all fall apart. Insulin signaling also regulates synaptic plasticity, serotonin production, acetylcholine balance, and BDNF. So poor metabolic signaling doesn’t only starve neurons it also makes them “forget how to learn.” Diabetes also increases levels of advanced glycation end products (AGEs), which are like sticky caramelized proteins that physically gunk up receptors, stiffen membranes, and activate inflammation. Blood vessel health declines, reducing oxygen delivery. Redox balance swings toward chronic oxidative stress. Over years, this combination erodes the frontal lobe, hippocampus, and basal ganglia structures tightly tied to memory, motivation, movement, and personality.

I’m wondering where everyone gets their injectible peptides from? Anthony, does SSRP have a preferred source that us in the community could purchase from? Any online clinic where a virtual consult could be done and the peptides prescribed from a compounding pharmacy and shipped to our residence? I have a functional medicine doctor in miami but he requires you pick them up and they are already reconstituted which affects their expiration.

A lot of people in this community are doing the work training, learning, cleaning up nutrition, experimenting with protocols yet still feeling like they’re not fully accessing the performance, clarity, energy, or momentum they know is inside them. It’s not because they’re missing discipline. It’s because they’re missing precision. Your physiology is speaking all the time. Recovery patterns, inflammation, redox shifts, sleep architecture, mitochondrial output these are signals. When you know how to interpret them, progress becomes inevitable. That’s where I come in. For the first time, I’m opening up clear paths for those who want deeper support and a guided transformation inside the Castore Core ecosystem. I take on only a handful of new clients each month to maintain the level of detail, personalization, and precision this work deserves. Option 1 Introductory Consults For the person seeking clarity, direction, or troubleshooting without a long-term commitment. These sessions do not include ongoing email support. Introductory Special $500 1-hour consult 30-minute follow-up Written notes + actionable plan This is the cleanest on-ramp to breakthrough momentum. Single Consult $350 1-hour targeted consult Strategic direction or troubleshooting Direct. Focused. High impact. Perfect if you want clarity right now but don’t need ongoing support. Option 2 Castore Core: Evolution Tier $600/month or $1500 paid upfront (3-month commitment) For those who want guided progress, accountability, structure, and steady forward movement without overwhelm. You get: 1-hour Zoom check-in each month Unlimited email support with a 48-hour turnaround Protocol refinements as your training, stress, and recovery evolve Evolution is where you take action and I help you sharpen the edge every step of the way. Not for: Those needing high-frequency access or rapid protocol iteration. Option 3 — Castore Core: Ascension Tier $1400/month or $3600 paid upfront (3-month commitment)

@Anthony Castore Your boy has been on my mind. Do we have any updates? Hope he’s doing amazing and recovering?!!! 🙏🏼💕 Avocado, my Mal, isn’t fully back, but a lot better. Appears to me it is a strain of some sort in his left hind leg. The CBD, love and attempt to keep him from being his spunky self seem to aid toward healing… 🙏🏼

Last night, I woke up to something that shook me in a way I haven’t felt in a long time. My bulldog Jeter, who’s ten now and basically my shadow, was shivering on the inhale while he slept. At first I thought maybe he was cold, or dreaming. Bulldogs dream with their whole soul, so that wasn’t unusual. But something felt off. The tremor wasn’t rhythmic like dreaming. It was sharp, almost like a nerve misfiring. When he got up from bed to walk to another room, he seemed weak like his legs weren’t receiving the normal signals from his brain. His shoulders and legs trembled slightly, his paws looked unsure beneath him, and he kept repositioning like he couldn’t get comfortable. That’s when my stomach dropped. I scooped him up, put him in the car, and Julie and I drove straight to MedVet. If you’ve ever loved a dog deeply, you know that feeling where you go from half-asleep to wide awake with one single thought: “Please let him be okay.” At MedVet they gave him a ketamine and methadone shot for pain, and they suspected a disc issue in his spine. They didn’t run an MRI that night, so we were left with the kind of diagnosis most dog owners get at first: “Likely disc compression, monitor closely.” In other words, an entire universe of things could be happening under the surface. When we finally got back home, Jeter was sedated, wobbly, and tremoring. He was trying to be strong bulldogs have a level of pride that honestly rivals ours—but he was struggling. And in moments like that, both as a practitioner and as a dog dad, you are forced to sit between two worlds: the scientific understanding of what’s happening, and the emotional weight of watching someone you love suffer. That’s what inspired me to write this for you today not just to share the story, but to teach you what’s actually going on inside a dog’s body when a disc bulges, why the symptoms show up the way they do, and how targeted regenerative peptides like Pentosan, ARA-290, TB-500, BPC-157, and SS-31 can create a powerful recovery pathway when used correctly.