Is there any difference between kenetic vs kenetic pro besides the amount of ketones? Are the tastes of the different flavors the same? When I calculate the per mg dose, the regular kenetic comes out to be a lot less expensive even when I use the discounted price that Anthony Castore offers through his buyers club. At higher doses, the Pro is more convenient, but not at a cost perspective.

Most people think muscle growth and mitochondria live in separate worlds. Muscle growth is about lifting heavy weights, eating protein, and activating anabolic pathways. Mitochondria are about endurance, cardio, and oxygen. One is for strength athletes and bodybuilders, the other is for runners and cyclists. That way of thinking is incomplete and it creates many of the problems people run into with stalled progress, chronic fatigue, poor recovery, and overcomplicated protocols that look impressive but quietly undermine long term adaptation. Muscle is not just a contractile tissue designed to move joints. It is a highly metabolically active organ system. Inside every muscle fiber are thousands of mitochondria producing energy, lipid membranes that organize signaling, redox systems that determine whether stress becomes adaptation or damage, and genetic machinery that decides what gets built next. A helpful way to think about muscle is as a city. The contractile proteins are the machinery, the mitochondria are the power plants, the membranes are the wiring and roads, and the nucleus is city hall making decisions. If the city builds bigger machines faster than it upgrades power plants and infrastructure, the system becomes fragile. That is exactly what happens when muscle growth outpaces mitochondrial adaptation. Mitochondria are often described as the powerhouse of the cell, but that description leaves out most of what makes them important. Mitochondria do not just make energy. They produce signaling molecules that tell the cell how to adapt. They help determine whether fuel comes from fat, carbohydrate, or amino acids. They influence inflammation, repair, and cell survival. They even provide structural support for signaling proteins through their membranes. Mitochondria are not passive batteries. They are decision making centers. A confusing paradox in training is that heavy resistance training improves mitochondrial function but often reduces mitochondrial density relative to muscle size. This does not mean resistance training is bad for mitochondria. It means muscle fibers can grow faster than mitochondria are built unless the right signals are included. An easy way to visualize this is to imagine drawing dots on a balloon. As the balloon inflates, the dots move farther apart. The dots did not disappear, but their density decreased. This is what happens when hypertrophy outpaces mitochondrial biogenesis.

Bile acids and estrogen are linked not because the body made a mistake, but because it is extraordinarily efficient. Human physiology is built around conservation. Anything energetically expensive or biologically powerful is reused whenever possible. Cholesterol is reused. Bile acids are reused. Steroid hormones like estrogen are reused. The liver and gut work together as a recycling plant, constantly deciding what to keep, what to modify, and what to throw away. Estrogen and bile acids happen to share the same conveyor belt. This is why problems with digestion, stool, gallbladder function, thyroid output, stress, or the microbiome so often show up as “hormone issues.” The hormones are downstream. The traffic system is upstream. To understand the connection, we start with the simplest possible truth: estrogen does not simply rise or fall on its own. Estrogen exposure is the result of production, conversion, binding, recycling, and elimination. Bile acids influence three of those five steps. That alone explains why anti-estrogen strategies so often fail. Bile acids are usually taught as digestive detergents. You eat fat, the gallbladder squeezes, bile comes out, fats get emulsified, end of story. That explanation is incomplete. Bile acids are also signaling molecules that talk directly to the liver, the gut, immune cells, and the microbiome. They regulate which bacteria survive. They turn genes on and off. They decide how aggressively the liver detoxifies hormones. Think of bile acids less like dish soap and more like traffic police. They don’t just clean up fat. They control flow. Estrogen’s journey through the body follows a predictable arc. Estrogen is synthesized or converted from precursors, used in tissues like breast, bone, brain, muscle, and reproductive organs, and then whatever is left over is sent to the liver. The liver’s job is not to destroy estrogen but to neutralize it temporarily. It does this by conjugating estrogen, mainly through glucuronidation and sulfation. These chemical tags make estrogen water-soluble and biologically quieter.

Peptides are often treated like supplements you can stack for convenience. One for repair, one for metabolism, one for inflammation. That mindset leads people to assume they can simply mix peptides in the same syringe and inject once. The problem is peptides are not pills. They are fragile, information-carrying molecules whose behavior is governed by physics, chemistry, and biology at the same time. A peptide is not just a chain of amino acids. In solution it exists as a three-dimensional structure held together by weak forces like hydrogen bonds, electrostatic interactions, and hydrophobic effects. These forces are highly sensitive to the environment. Small changes in pH, ionic strength, or solvent conditions can change the peptide’s shape, stability, and behavior. When a peptide is manufactured, it is stabilized in a very specific formulation. That formulation controls pH, charge, ion balance, and solubility so the peptide stays folded correctly and remains biologically active. When you mix two peptides together, you destroy that controlled environment and create a new, untested chemical system. One of the first things that goes wrong is charge balance. Peptides carry electrical charge depending on pH. That charge helps keep molecules from sticking to each other. Mixing peptides can shift pH just enough to reduce repulsion between molecules. When repulsion drops, attraction wins, and peptides begin to stick together. Ionic strength matters too. Mixing solutions often increases ion concentration, which compresses the electrical “buffer” that keeps peptides apart. This allows molecules to drift close enough for hydrophobic regions to interact. Water dislikes exposed hydrophobic surfaces, so peptides clump together to lower free energy. This is basic solution physics. Once aggregation starts, it accelerates. A few misfolded molecules form a nucleus, which seeds further aggregation. Early clumps may be invisible, but they still matter. They reduce the amount of active peptide, alter absorption, and change signaling behavior.

Hey Everyone, just in an effort to share this and others benefit from it I ordered my monthly blood labs for first time from GoodLabs.com that I’ve been getting from PrivateMDLabs, or Ulta Labs most recently… Pricing for same lab from each provider: PrivateMD = $954 Ulta = $732 GoodLabs = $409 And GoodLabs offers an at home visit for an extra $100 if that’s worth it for you