Jan 1 • Nutrition 101
WHY ACTIValoe® IS IN COLLAGEN+
WHY ACTIValoe® IN COLLAGEN+ (and why “aloe” isn’t always aloe)
Aloe is one of the most misunderstood “gut health” ingredients—because what people call “aloe” can include very different parts of the leaf, and those parts behave very differently in the body.
The key distinction:
- Inner leaf gel / mucilage fraction → rich in polysaccharides (often used for “soothing” GI support)
- Latex / outer leaf fraction → contains anthraquinones like aloin (the classic “laxative” effect)
This matters for safety and consistency.
The International Aloe Science Council (IASC) states their standard for aloin in products for oral consumption is <10 ppm.
And FDA ruled aloe (as a stimulant laxative ingredient) is not generally recognized as safe and effective for OTC laxative drug products due to inadequate safety data (this is specifically about stimulant laxative use, not “food-grade gel”).
EFSA has also raised concerns around hydroxyanthracene derivatives (a category that includes aloe-emodin–type compounds) regarding genotoxicity/carcinogenicity risk in food contexts—another reason the industry focuses on keeping these compounds very low.
Translation: the “type” of aloe—and the processing/standardization—matters.
Why we prefer ACTIValoe® (safety + efficacy logic)
In Collagen+, we use patented ACTIValoe® (Aloe Corp), and we chose it for 3 main reasons:
1) It’s standardized for the active gel fraction (polysaccharides)
Aloe Corp states ACTIValoe® is the only supplier to quantify and guarantee 10% polysaccharide retention (dry weight) through its patented process and that they enhance polysaccharide content in a specific molecular range (50,000–200,000 Daltons).
Why that matters: botanical ingredients are naturally variable. Standardization is how you get repeatability.
2) It’s built around content + purity aligned with IASC standards
Aloe Corp states ACTIValoe® exceeds IASC certification standards for content and purity.
And IASC’s own FAQ clarifies the <10 ppm aloin standard for oral aloe products.
3) It supports the “gut-first” intent of Collagen+
Collagen+ explicitly frames ACTIValoe® + fulvic acid as part of the “Plus Difference” designed to maximize collagen absorption while promoting a healthy gut environment.
Why aloe + multi-type collagen is a smart combination
Collagen+ isn’t just “collagen peptides.” It’s designed around a gut → connective tissue → skin/joints axis.
Collagen (the building blocks)
There’s strong evidence from systematic reviews/meta-analyses that oral hydrolyzed collagen can improve skin hydration and elasticity compared to placebo.
There’s also supportive evidence (review-level) that collagen peptides can improve joint pain/function outcomes in various populations.
Aloe (the gut terrain + comfort support)
Human clinical research suggests aloe gel syrup may help reduce GERD symptoms and is generally well tolerated over 4 weeks in a randomized controlled trial.
And specific aloe fractions like aloe sterols have been studied for skin elasticity/hydration in randomized, placebo-controlled trials.
Our “faith + function” takeaway:
We’re supporting both:
- structure (collagen peptides = building blocks), and
- environment (standardized aloe gel fraction + gut-first absorption strategy)
How to use Collagen+ (simple + consistent)
Directions on the sheet: 1 heaping scoop in 8+ oz hot or cold beverage; use once daily or more depending on goals/routine.
Summary:
• “Aloe” isn’t one thing—inner gel ≠ latex. Latex contains anthraquinones (like aloin) that drive laxative effects; quality aloe focuses on keeping that fraction very low.
• ACTIValoe® is a patented, standardized aloe ingredient designed for content + purity + consistency, with a stated guarantee on polysaccharide retention.
• Collagen+ uses ACTIValoe® + fulvic acid as part of a gut-first absorption strategy (per product sheet). 
• Evidence base: collagen peptides have strong clinical evidence for skin hydration/elasticity, and supportive evidence for joints; aloe gel has human data for GI comfort (e.g., reflux/GERD symptoms).
FAQ
Q: Isn’t aloe basically a laxative?
A: It can be—if you’re using the latex/outer-leaf fraction, which contains anthraquinones (like aloin) associated with stimulant-laxative effects. IASC notes the oral-consumption standard for aloin is <10 ppm, and EFSA has raised safety concerns around hydroxyanthracene derivatives—this is why sourcing/processing matters.
Q: What is “aloin,” and why do we care?
A: Aloin is one of the key anthraquinones in aloe that’s linked to the laxative fraction. Quality aloe ingredients aim to keep it very low (or remove the latex fraction).
Q: Why not just drink aloe vera juice from the store?
A: Many are fine, but the category is variable. The differences come down to processing, purity, standardization, and aloin control. We prefer ACTIValoe® because it’s positioned as standardized (polysaccharide retention) and aligned with IASC quality standards—more consistency, less guesswork.
Q: What’s the “gut-first” logic in Collagen+?
A: The Collagen+ sheet specifically frames ACTIValoe® + fulvic acid as part of an approach intended to promote a healthy gut environment and maximize collagen absorption.
Q: What benefits should someone realistically expect from collagen?
A: The strongest human evidence supports improvements in skin hydration and elasticity with hydrolyzed collagen, based on systematic reviews/meta-analyses of RCTs. Joint outcomes are supportive but can vary by population and formula.
Q: What benefits are supported for aloe (oral)?
A: Human clinical studies suggest aloe gel preparations may help support GI symptoms like reflux/GERD in some people, and specific aloe fractions (like sterols) have been studied for skin measures—but product type and standardization matter.
Q: Any safety cautions?
A: Yes—avoid stimulant-laxative aloe forms and stop if you get cramping/diarrhea. FDA removed aloe latex from OTC laxative products due to insufficient safety data, and EFSA has cautioned on hydroxyanthracene derivatives—both reinforce “quality + processing” as non-negotiable.
Collagen plus: https://bedrocknutrition.idlife.com/shop/product/15-0104
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WHY ACTIValoe® IS IN COLLAGEN+
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