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BIOHACKING WITH TONY HUGE

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The Peptide Community

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25 contributions to BIOHACKING WITH TONY HUGE
First Stack
Hey guys, I’m new here and found Tony on YouTube and was more than impressed by all of his knowledge on supplementation. I’ve been lifting for about 13 years now and I’m just looking to get to the next level. I’m 5,11, 215lbs 17% body fat at the moment and I’m looking to start my first stack. I’ve heard a good start is the “Trinity Stack” (Mk677, Ac262, and Enclomiphene). I’d appreciate any helpful insight on this stack and if you recommend anything else?? Also I have adhd like crazy and have a trouble time focusing and finishing things so I’m looking into a good beginner nootropic peptide or something else that I could possibly throw in with this stack! Nice to meet everybody btw! 👋
0 likes • 12d
@Trey Wilson Interesting. When you take that high of a dose of test, do you have much side effects? Do you need to take any anastrozole? Do you use Hcg as well?
0 likes • 11d
@Trey Wilson Thanks. Seems like you have found something that works well for you.
Fertile on enclo + trt?
I know that many guys become infertile after a while on trt, and that sometimes hcg and/or enclo can be used to help with that, but what if I am already on enclo with good results, do I have less of a chance of becoming infertile once starting trt? In other words what makes more sense on paper for fertility: 1. Enclo first then trt 2. Trt first then enclo I’d like to stop enclo all together and just do trt eventually but we want more kids so that isn’t an option yet.
2 likes • 13d
Many men choose to use Hcg while on TRT. Some men try to use gonadorelin, but it does not seem to work as well while on TRT. TRT has a strong shut down effect on LH and FSH. Some men also use Hmg and Kisspeptin-10 to improve fertility.
Kisspeptin-10 instead of Enclomiphene?
Wanted to open a discussion on kisspeptin-10 as an alternative to enclomiphene. Since my experiences with enclomiphene has been a bit mixed. Might have been a timing and dosing issue, but from my research it appears kisspeptin-10 might be an even better option for the reasons I outline below. The problem with enclomiphene for some guys: - Works by blocking estrogen receptors to force LH upward - But estrogen does a lot more in the male brain than just hormonal feedback - Regulates mood, sleep quality, dopamine sensitivity, and libido directly - Block those receptors and you lose all of that simultaneously - Result for sensitive nervous systems: wired, tired, flat affect, poor sleep, reduced libido - The mechanism is rarely discussed, just the hormonal numbers Why kisspeptin-10 looks interesting: - Stimulates GnRH directly, drives natural LH and FSH without touching estrogen receptors - Estrogen signalling fully preserved, none of the neurological cost - Stimulates FSH as well as LH, more complete than enclomiphene - fMRI research shows direct limbic system activation for sexual desire, independently of testosterone changes - Compatible with daily micro-dosing, potentially better for guys who respond poorly to amplified intermittent hormonal signals The evidence base is stronger than most people realise: - Kisspeptin-10 has substantial peer-reviewed clinical research behind it, primarily from reproductive endocrinology and fertility medicine - Imperial College London in particular has published extensively on its effects in humans, this isn't animal data or theoretical, it's actual human trial evidence Keen to hear anyone's experiences on any of the following: - Has anyone actually run this subcutaneously? - What dose and frequency worked? - Did you notice libido or hormonal response and how quickly? - How did it compare subjectively to enclomiphene or clomiphene? - Any unexpected effects? Would really value Tony's perspective on whether this is a viable option or whether there are concerns worth addressing.
1 like • 25d
Also, considering that enclomiphene can reduce IGF-1, it's probably a good idea to use CJC/Ipamorelin while on enclo.
1 like • 18d
Very good video. Thank you!
Sleep Is the Number One Performance Drug – Here's How to Hack It After 30
Sleep is when most GH is released by your pituitary. It's necessary for recovery, muscle growth, and cognitive function. But after 30, your GH pulse flattens, and your pineal gland starts calcifying. Translation: your sleep quality tanks, and you don't even realize it. My new book breaks down the Sleep & Longevity Stack: Ipamorelin: Restores deep slow-wave sleep (the actual restorative phase) Epitalon: A twice-yearly peptide that lengthens telomeres and resets your biological clock This isn't melatonin. This is biological engineering. Question for the group: On a scale of 1 to 10, how restorative is your sleep right now? What's the biggest thing screwing it up? Free ebook – Sleep & Longevity Protocol Environment hacks, peptides, and pharmaceuticals. http://tonyhuge.is/miracle-now
0 likes • May 31
Perhaps about a 6. It's harder to get high quality sleep as we get older.
0 likes • 29d
@Tony Huge I believe it usually takes too long to fall asleep. Waking up too early is also common.
Ac262 suppression and ED on Enclomiphene.
I did an 8 week cycle on AC262 at 20mg/day. Along with AC262 I took Top T to try and keep my test levels around the same level before hoping on AC. 2 weeks after my AC cycle I took a testosterone test and found out that AC had really suppressed me. Ok admittedly I already had low-ish testosterone before and I think that is where I have screwed up. I was at 375 before and my last test after my ac cycle I am now at 215. So, I decided to hop on enclomiphene to try and raise my test levels back up. I started it last Thursday at 6.25 mg/day but I am now experiencing quite bad ED. For reference I am 23 years old and in relatively healthy shape and have never had issues with erectile dysfunction before. Not really sure what to do, should I carry on with the enclomiphene and hope my ED problems go? Or do I stop everything and cold turkey with hopes my body will naturally return to baseline? Thanks guys.
1 like • May 31
You might also consider testing LH, FSH, free testosterone, SHBG, estradiol and prolactin to get more details on your issue. Some men prefer the enclo every other day. Encl might possibly reduce IGF-1 so you can get that tested as well and use CJC/Ipamorelin if needed. If you have problems getting it resolved, then you can find doctors who specialize in hormones and peptides.
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Virgil Moore
3
41points to level up
@virgil-moore-9505
I like health and fitness and working out. I have started using peptides and want to make sure I have good information to use them correctly.

Active 1d ago
Joined Mar 10, 2026
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