Breaking Down Energy Peptides: My Complete Tier List
Hey everyone, I wanted to try something different today and create a comprehensive tier list breaking down the most popular energy peptides in the research space. PSA Much Better On Substack: https://derekpruski.substack.com/p/breaking-down-energy-peptides-my If you've been following my work at PeptidePrice.store, you know I'm all about transparency and helping people make informed decisions. So I thought it would be valuable to share exactly how I view these compounds and why I rank them the way I do. Understanding Energy Peptides Before we dive into the rankings, let's clarify what we're talking about. Energy peptides primarily work through two mechanisms: 1. Mitochondrial optimization - Improving ATP production and reducing oxidative stress 2. Metabolic enhancement - Increasing NAD+ levels and improving glucose utilization These compounds don't give you a caffeine-like jolt. Instead, they work at the cellular level to improve your body's fundamental energy production systems. My Energy Peptide Tier List 🔴 S Tier (Best-in-Class) SS-31 (Elamipretide) This is the gold standard for mitochondrial protection. SS-31 is a potent mitochondrial protector that enhances ATP output while reducing oxidative stress. The research behind this compound is incredibly robust, and it's specifically designed to target damaged mitochondria. If you're serious about cellular energy optimization, this belongs at the top of the list. MOTS-C A mitochondrial-derived peptide that directly boosts ATP production and increases glucose utilization. What I love about MOTS-C is its dual action - it not only improves energy production but also helps with metabolic efficiency. Perfect for those looking for "clean" energy without the crash. 🟠 A Tier (Excellent) 5-Amino-1MQ This one works differently - it inhibits NNMT, which leads to higher NAD+ levels. The result is increased metabolic rate and sustained energy. It's not quite S-tier because it's more indirect in its mechanism, but the NAD+ boost alone makes it incredibly valuable for energy optimization and fat loss support.