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337 contributions to Peptide Price
Weight Loss
This weight is absolutely melting off of me and i need it to slow down lol. I’ve gotta focus on my eating more cuz i weighed in at 184 today and started 220 in november.
0 likes • 3h
@Phillip Gavin I’ve seen other examples of people who are generally fit and more in shape respond really quickly to Reta. Looks like you have an athletic background so I’m guessing you are a strong responder.
0 likes • 52m
@Phillip Gavin well now you can expand your research and get on some Ipamorelin and CJC-1295.
Tesamorelin Storage Study Update: We're Running It 🔥
A lot of you have been following the debate about whether research-grade tesamorelin should be refrigerated or stored at room temperature after reconstitution. For those just catching up: most peptides go in the fridge after you mix them. But tesamorelin might be an exception. The FDA-approved version (EGRIFTA WR) specifically says room temperature storage. Josh Holyfield, a creator in this space, argues that research-grade tesamorelin follows the same rules because the molecule itself has properties that cause it to clump together when cold. His position is that standard purity testing won't even catch this because the issue is physical aggregation — molecules binding to each other — not chemical breakdown of the amino acid chain. Fair argument. But I'd rather have data than debate. So I called Kris at Freedom Diagnostics. We're doing the study. Here's the plan: we're taking reconstituted tesamorelin and splitting it into two samples. One stored at room temperature, one refrigerated. Then we test both over time. I also asked Kris to get input from other chemists on the theory that cold temperatures cause the amino acids to aggregate and make tesamorelin ineffective. His initial take was interesting — if physical aggregation is happening, we should see a measurable difference in overall mass over time and likely some shift in purity as well. That's not a final answer. That's a starting point. We'll let the results speak. What I want you to take away from this: This community has always been about transparency. I'm not a chemist. I'm not going to pretend I know more than people who study this for a living. What I can is get the testing done, and bring you the results. If the data shows refrigeration is a problem, I'll say so. If it shows room temp is better, I'll say that too. If it's somewhere in the middle, you'll see that as well. I'm also hoping to get Kris on a Podcast after the study wraps so we can walk through the findings together and answer your questions live.
Tesamorelin Storage Study Update: We're Running It 🔥
0 likes • 24h
@Derek Pruski I’ll go in with you and underwrite half if you want to go bigger. I can contribute from my RUO tesa stock as well.
0 likes • 24h
@Derek Pruski ok. My offer includes lab costs and samples. Let’s see where it goes.
Tesamorelin
Just got this email from Omegamino. This is going crazy right now. People are all over the place with weather or not to refrigerate! Can’t wait for the results from Derek’s study!!
Tesamorelin
1 like • 2d
I am so surprised that people (especially Chase Irons) are not doing a little bit of background checking to see protocol all comes from Egrifta WR which is a special formulation and not RUO Tesamorelin.
Back + Shoulders Workout @ Absolute Recomp In Frisco, TX
Yesterday, I showed off the tour of the Absolute Recomp In Frisco, TX. I was able to get a back and shoulders day workout in, and just thought it'd be cool to share with you guys. Huge shout out to one of my friends Tyler Johnson, who's also an affiliate with Peptira for recording. He made me feel right at home and drove over an hour and a half to meet up on Thursday night! If you're on TikTok, shoot him a follow here: https://www.tiktok.com/@tyler_johnson__?lang=en
Back + Shoulders Workout @ Absolute Recomp In Frisco, TX
1 like • 2d
Beast Mode: ON 🔥
Tesamorelin Storage Debate: Let's Get Real Data
Quick background for those new here: Most peptides should be stored in the fridge after you reconstitute them (mix them with bacteriostatic water). Cold temps help keep them stable longer. But tesamorelin might be different. The FDA-approved version (EGRIFTA WR) actually says to store it at room temperature — not in the fridge. Josh Holyfield, a creator in this space, argues that research-grade tesamorelin should follow the same rule because the molecule itself doesn't like cold temperatures. Something about its structure causes it to clump up and degrade when it gets cold. I pushed back on this in an earlier post. Josh responded with some solid points about the science behind it. Honestly? I don't know who's right. And I'd rather have real data than keep guessing. So here's what I'm going to do: When I get back to Denver, I'm sending a vial of tesamorelin to Freedom Diagnostics for a 4-week degradation study. This will show us exactly what happens to research-grade tesamorelin under different storage conditions. No more theories. Just actual results. I'll keep you all posted.
Tesamorelin Storage Debate: Let's Get Real Data
7 likes • 3d
@Jeff Hunter @Derek Pruski I’ve continued to look into this also. His video asserts that the reason why Tesa needs to be handled differently is that there is an intrinsic amino chain-length-driven solubility inversion mechanism in refrigeration. I searched and the only documented examples of true inverse solubility (cold-induced aggregation) is in elastin-like peptides, certain hydrophobic repeat sequences, and some polymers. Tesa is not any of these. Tesamorelin is 44 amino acids, but is not an elastin-like peptide, does not have a known LCST (lower critical solution temperature) behavior published in the literature. There is no peer-reviewed evidence showing tesamorelin has an intrinsic, sequence-driven solubility inversion purely because of chain length. So: chain length alone does not cause cold-induced gelling. So while clouding/aggregating/clumping can occcur with Tesa it is not scientifically shown to be for the reasons he identifies. So the problem is a garden variety clumping issue: too much concentration of peptide, bad pH, reduced molecular movement at low temps, lack of stabilizing excipients. What’s being described in the video is a real phenomenon being given the wrong universal explanation. • The observations (clouding, thickening, aggregation when cold) can be real. • The mechanism (intrinsic chain-length-driven solubility inversion) is not established in peer-reviewed research • The conclusion (all tesamorelin should avoid refrigeration) does not follow.
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Barry Freeman
6
1,174points to level up
@barry-freeman-5769
Husband, father of 3 boys, on a fitness journey

Active 11m ago
Joined Oct 4, 2025