Just added Cartalax to the research stack I will let you know if I see any improvements. Been curious about this one for a while and my research to have some hamstring issues while training. My approach is always low and slow with everything, but I’ll keep you guys updated as time goes on!

The results are starting to come in. For those just joining: there's been a debate in the peptide community about whether research-grade tesamorelin should be stored at room temperature or refrigerated after reconstitution. Instead of arguing theory, I partnered with Freedom Diagnostics to run an actual degradation study. Here's how it works: We took two identical samples of reconstituted tesamorelin. One stays at room temperature. One goes in the fridge. Both get tested once a week for four weeks. Initial baseline results: - Sample 1: 99.24% purity - Sample 2: 99.25% purity Essentially identical starting points — exactly what we need for a fair comparison. I've attached the original COA so you can see the data for yourself. Over the next four weeks, we'll track whether purity holds, drops, or differs between the two storage methods. No speculation. Just numbers. Big shoutout to Ion Peptides for providing the samples for this study. I'll post updates each week as new results come in. Appreciate everyone following along — this is how we get real answers.

Just got this email from Omegamino. This is going crazy right now. People are all over the place with weather or not to refrigerate! Can’t wait for the results from Derek’s study!!

Quick background for those new here: Most peptides should be stored in the fridge after you reconstitute them (mix them with bacteriostatic water). Cold temps help keep them stable longer. But tesamorelin might be different. The FDA-approved version (EGRIFTA WR) actually says to store it at room temperature — not in the fridge. Josh Holyfield, a creator in this space, argues that research-grade tesamorelin should follow the same rule because the molecule itself doesn't like cold temperatures. Something about its structure causes it to clump up and degrade when it gets cold. I pushed back on this in an earlier post. Josh responded with some solid points about the science behind it. Honestly? I don't know who's right. And I'd rather have real data than keep guessing. So here's what I'm going to do: When I get back to Denver, I'm sending a vial of tesamorelin to Freedom Diagnostics for a 4-week degradation study. This will show us exactly what happens to research-grade tesamorelin under different storage conditions. No more theories. Just actual results. I'll keep you all posted.

There's been some fear mongering circulating because a creator made a video saying you shouldn't refrigerate Tesamorelin. Here's the thing—he was talking about Egrifta, the pharmaceutical version. Not the same situation. Huge shout out to @Barry Freeman for digging into this further. Let me break down why RUO Tesa is fundamentally different and why you should absolutely still refrigerate it like every other lyophilized peptide. Same Active Ingredient ≠ Same Product Yes, Egrifta and RUO Tesamorelin share the same active ingredient. But Egrifta is an FDA-approved product held to a much higher standard for purity, excipients, endotoxins, and stability. This is exactly why context matters—"gray market" products, while chemically similar, a lot of the times don't have the same stabilization ingredients. RUO tesamorelin is not manufactured under drug GMP the way an FDA-approved product is. Even when a vendor provides a COA, it may not cover the same parameters, not to the same standard, and sometimes not even for the final vial you receive. (Common problem: testing a bulk batch, then aliquoting later.) Why Egrifta Doesn't Need Refrigeration EGRIFTA WR isn't just peptide in BAC water. It's a deliberately engineered formulation: - Hydroxypropyl-β-cyclodextrin → stabilizes peptide conformation - pH tightly buffered (≈4.5–7.4) This formulation was stress-tested during FDA stability studies at room temperature for 7 days. Refrigeration wasn't required to preserve potency within that validated window. The product was specifically engineered so refrigeration adds no benefit—and may actually introduce instability through temperature cycling, condensation, or crystallization effects. The Bottom Line Your RUO Tesamorelin doesn't have that sophisticated stabilization system. It's a lyophilized peptide like any other, and it should be treated like one. Refrigerate it. Don't let a video about a completely different product change how you handle your research materials. Context matters.