Most people talk about GLP-1s in terms of weight loss and appetite suppression—but the mental effects can be just as big. For many, food isn’t just fuel 🍔➡️🧠. It’s also a coping mechanism. The dopamine hit from eating becomes a “go-to” for comfort, stress relief, or even boredom. When GLP-1s step in and dull appetite, they don’t just cut hunger—they disrupt that reward loop. And that can feel strange. Some people report: - Feeling a sense of “emptiness” or boredom because food no longer provides the same satisfaction. - Looking for something else to fill that dopamine gap. - Replacing food habits with new ones (sometimes healthier, sometimes not). 👉 This is where being intentional matters. If you know that the dopamine fix will try to reroute itself, you can choose where it goes: - 💪 Working out or movement - 🎨 Creative projects or learning - 💬 Deepening relationships - 🧘 Stress-relieving practices The risk is letting that fix slide into negative replacements—doomscrolling, drinking, or other compulsive habits. But the opportunity is channeling it into something that builds you up. This is also where tracking helps 📊. Logging your peptide protocols, mood, or daily habits in Stack Tracker can make patterns clearer—like whether energy and motivation are shifting into positive outlets or sliding toward distractions. Sometimes just seeing it laid out visually makes all the difference. And you don’t have to figure this out alone. Our community on Skool is where people share what they’ve noticed on these compounds. You may find others going through the exact same shift—or even help someone realize they’re experiencing it without knowing why. 💬 Question for the group: If you’ve run GLP-1s, did you notice your relationship with food shifting into other areas of life? How did you channel that change? Stay Informed: 🌐 Stacktracker.info | 🎥 Rumble Channel | 👥 Join the discussion here

In the past 30 days, the research peptide industry has seen a wave of legal developments—including lawsuits, government enforcement, and several new regulations affecting production, sales, and clinical use. 🏭 Manufacturer Lawsuits & FDA Enforcement - Eli Lilly filed multiple lawsuits against telehealth companies and compounding pharmacies in California federal court, alleging they were selling compounded GLP-1 drugs (like tirzepatide) without FDA approval following the end of the FDA’s shortage designation in 2025. - The FDA has stepped up enforcement, sending warning letters to peptide sellers who market unapproved peptides (notably semaglutide and tirzepatide) for human use under “research only” labels, threatening seizures, injunctions, and criminal referrals. - Enforcement is now targeting manufacturers and supply chains, focusing on GMP, sterility, and traceability—especially for “research use only” (RUO) operations. 🌐 State Crackdowns on Grey Market Peptides - Ohio state medical and pharmacy boards suspended several medical spa licenses for administering non-FDA-approved peptides, highlighting a national trend of state-level crackdowns. - Providers using “grey market” peptides face heightened risk, from license suspensions to civil or criminal charges, if they use unapproved compounds in patient care. ⚖️ Mass Torts & Major Lawsuits - Multidistrict litigation against Novo Nordisk for Ozempic and other GLP-1 drugs has surged, with nearly 2,000 active cases alleging defective drug claims and harmful side effects in the past 30 days. 📜 Regulatory Guidance & Compounding Law - As of January 2025, new FDA rules limit bulk substance use by compounding pharmacies. Only peptides on the FDA Bulks List—or those meeting strict FDA criteria—may be compounded. - FDA enforcement is focusing heavily on marketing claims. Peptides labeled RUO cannot be legally compounded or sold for human use, even with disclaimers. Providing syringes or injection instructions alongside RUO peptides has also triggered warning letters.

When people talk about peptides, the focus is usually on dosing, half-lives, or stacking. But one of the biggest amplifiers—or limiters—of results is something far simpler: sleep. Here’s why sleep matters so much when running peptide protocols: - Growth hormone release peaks during deep sleep 💤GH secretagogues (CJC-1295, Ipamorelin, etc.) are designed to boost natural pulses, but if deep sleep is cut short, you’re stacking on top of a weak signal. - Repair & recovery happen overnight 🦴Peptides like BPC-157 and TB-500 are all about repair. Without quality sleep, the body doesn’t shift into the full regenerative state it’s designed to support. - Immune regulation needs circadian rhythm 🌙Compounds like Thymosin Alpha 1 align with immune cycles, which are heavily tied to sleep quality and timing. - Metabolic peptides perform differently under sleep debt ⚖️GLP-1 agonists like Semaglutide may help regulate appetite, but poor sleep still throws hunger hormones (ghrelin/leptin) out of balance. 👉 The takeaway: Peptides can amplify a signal, but sleep provides the foundation. Without restoring the circadian rhythm, the stack may only take you halfway. This is also why tracking protocols alongside lifestyle factors (like sleep quality, fasting windows, or stress) is so important. Tools like Stack Tracker make it easier to see whether your protocol is fighting against—or working with—your sleep. 💬 Question for the group: Have you noticed peptides working better (or worse) depending on how well you’ve been sleeping? What changed for you?

One of the most overlooked parts of running a peptide protocol isn’t the dosing or the timing—it’s the nutritional environment you create around it. Think about it like this: peptides are signals 📡. They tell your body to do something—release growth hormone, repair tissue, modulate immune response. But if the raw materials aren’t there, the signal doesn’t translate into results. A few examples: - GH secretagogues (CJC-1295, Ipamorelin): ⚡️ Work best when insulin is low. Running them after a carb-heavy meal 🍞 can blunt the response. - Repair peptides (BPC-157, TB-500): 🦴 Rely on amino acids, minerals, and hydration 💧. If protein intake is low, recovery may stall. - Metabolic peptides (GLP-1s like Semaglutide or AOD-9604): ⚖️ Nutrition can make or break these—poor diet choices 🍔 can mask the benefits. - Longevity compounds (Epitalon, MOTS-C): ⏳ Effects often compound when paired with consistent micronutrient support 🥕. It’s also worth noting that timing meals ⏰ around protocols can change outcomes. Fasting windows, carb timing, and even hydration can all shift how effective a stack feels. This is why tracking matters 📊. If your nutrition changes but your results shift, how do you know if it was the peptide or the diet? Tools like Stack Tracker make it easier to log both protocols and observations so you can spot patterns over time. 👉 Question for the group: Have you ever noticed your nutrition either amplified 🚀 or blunted 🛑 the results of a peptide protocol? What changed when you dialed in your diet?

The daily mobility course is uploaded with videos and coaching cues. These are four drills that I really prioritize, but I’ll keep adding to this specific library as I continue to grow this community. The best thing you can do for me is share this course with someone and encourage them to join this entirely FREE community. Thanks! https://www.skool.com/notmarksanchez/classroom/e9c90e80