🧠 The Mental Side of GLP-1s (Semaglutide, Tirzepatide, Retatrutide)
Most people talk about GLP-1s in terms of weight loss and appetite suppression—but the mental effects can be just as big.
For many, food isn’t just fuel 🍔➡️🧠. It’s also a coping mechanism. The dopamine hit from eating becomes a “go-to” for comfort, stress relief, or even boredom.
When GLP-1s step in and dull appetite, they don’t just cut hunger—they disrupt that reward loop. And that can feel strange. Some people report:
  • Feeling a sense of “emptiness” or boredom because food no longer provides the same satisfaction.
  • Looking for something else to fill that dopamine gap.
  • Replacing food habits with new ones (sometimes healthier, sometimes not).
👉 This is where being intentional matters. If you know that the dopamine fix will try to reroute itself, you can choose where it goes:
  • 💪 Working out or movement
  • 🎨 Creative projects or learning
  • 💬 Deepening relationships
  • 🧘 Stress-relieving practices
The risk is letting that fix slide into negative replacements—doomscrolling, drinking, or other compulsive habits. But the opportunity is channeling it into something that builds you up.
This is also where tracking helps 📊. Logging your peptide protocols, mood, or daily habits in Stack Tracker can make patterns clearer—like whether energy and motivation are shifting into positive outlets or sliding toward distractions. Sometimes just seeing it laid out visually makes all the difference.
And you don’t have to figure this out alone. Our community on Skool is where people share what they’ve noticed on these compounds. You may find others going through the exact same shift—or even help someone realize they’re experiencing it without knowing why.
💬 Question for the group: If you’ve run GLP-1s, did you notice your relationship with food shifting into other areas of life? How did you channel that change?
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John Bastiat
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🧠 The Mental Side of GLP-1s (Semaglutide, Tirzepatide, Retatrutide)
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