HBOT and Hydrogen Therapy: A Synergistic Combination

Bernardo explored the synergistic potential of combining Hydrogen Therapy with Hyperbaric Oxygen Therapy (HBOT).

HBOT increases oxygen and ROS (reactive oxygen species), which can be damaging if unchecked.

Hydrogen therapy (H₂), especially when timed post-HBOT, selectively neutralizes harmful ROS (like hydroxyl radicals) while sparing beneficial ones (like H₂O₂), supporting cellular healing without blunting HBOT effects.

Hydrogen preconditioning before HBOT may help reduce oxidative stress in sensitive individuals, while post-HBOT use may enhance recovery and reduce inflammation.

✅ Supplements & Compounds

● Hydrogen Therapy (H₂):

○ Forms: Hydrogen-rich water, Hydrogen gas inhalation.

○ Functions:

■ Scavenges harmful ROS

■ Protects mitochondria

■ Reduces inflammation

■ Enhances oxygen utilization

■ Supports long-term therapeutic gains

● Complementary Compounds Mentioned:

○ Metformin (used by Christine Michaud, monitored during HBOT)

○ Betulinic Acid (recommended by Thomas Petracca, citing Dr. Peavler’s video)

■ Proposed as more potent than DON for glutamine suppression

■ Dose: ~6–8g/day (250mg caps)

✅ Therapies & Strategies

● HBOT (Hyperbaric Oxygen Therapy):

○ Enhances tissue oxygenation

○ Increases ROS for signaling and repair

● Hydrogen Therapy adds:

○ Protection from HBOT-induced oxidative stress

○ Complementary anti-inflammatory and mitochondrial support

● Combined use recommended especially for:

○ Cancer

○ TBI, Alzheimer’s, Parkinson’s

○ Chronic inflammation

○ Post-exercise muscle recovery

● Caution:

○ Avoid combining hydrogen with high-dose oral antioxidants (e.g., Vitamin C) too close to HBOT to preserve oxidative benefits.

✅ Lab Testing & Data Gaps

● Glucose Monitoring: Christine mentioned her clinic tests glucose pre-HBOT to avoid hypoglycemia when using Metformin.

● No direct clinical trials yet comparing before vs. after hydrogen use, but literature supports timing-dependent modulation of ROS.

✅ Resources & References Shared

● Dr. Peavler video on Betulinic Acid vs. DON

● Hydrogen therapy info via AquaCure AC50 machine (used by several members)

● Clarification on Kangen water vs. Hydrogen-rich water

○ Kangen = alkaline water

○ Hydrogen-rich water = contains dissolved molecular hydrogen (H₂) with direct ROS-scavenging properties

○ More scientific data exists on hydrogen water/gas for oxidative damage protection

✅ Key Takeaways

● 6-8h Post-HBOT hydrogen therapy appears to enhance recovery by minimizing excessive oxidative stress while preserving HBOT’s benefits.

● Pre-HBOT hydrogen therapy may offer mitochondrial protection and reduce baseline inflammation in sensitive individuals.

● Dual timing strategy (pre and post-HBOT) could offer full-spectrum benefits, but must be carefully timed.

● Cost-effective hydrogen options (vs. expensive Kangen systems) are available and supported by growing research.

● Betulinic Acid is a promising, affordable alternative to DON with strong glutamine-suppression effects.

● Avoid antioxidant overload near HBOT sessions — balance is key.

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