THC doesn’t create your state — it amplifies it.

Saint Campodonico

19d • Daily Dose

When you’re stressed, your sympathetic nervous system (SNS) is active.

This increases:

• cortisol

• heart rate

• amygdala activation

• internal tension

• shallow breathing

A 2017 Harvard study showed that stress changes the way THC interacts with CB1 receptors, making sensations feel sharper, faster, and more overwhelming.

When you're calm, parasympathetic activity (rest & digest) dominates — so THC feels:

• smoother

• grounding

• more predictable

• more enjoyable

THC interacts with your state, not just your brain.

How does cannabis feel in your body when you're stressed vs calm?

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