The Methylation Hub

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2d •

Released only to the first 50 at a founding price of 59 USD. Interested but not sure if it is for you? Here is a preview of the Handbook ⬇️ In this book, you will find the exact method I use in my daily practice. The test I recommend The supplements. The common Pitfalls The red flags. Everything you need to know based on my 25 years of clinical experience Want to see the rest and own the full copy forever? Join the classroom

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Jean-marc Sobczyk

Mar 17 •

Start Here

📌 START HERE — Read This First

You got an MTHFR result. Then what? For most people, that moment goes one of two ways. Your doctor glanced at it and said, "It's not clinically significant." Or you fell down a rabbit hole of contradictory websites, Facebook groups, and supplement protocols that left you more confused than when you started. Neither of those should happen. That's exactly why this community exists. I'm Jean-Marc — integrative physician, 25 years in clinical practice, and probably the only doctor you'll meet who gets genuinely excited about methylation genetics. I created The Methylation Hub because the gap between what the science tells us and what patients actually receive is one of the most unnecessary failures in modern medicine. You deserve better than a shrug or a supplement shopping list. This is what you'll find here Clinical depth without the jargon. Evidence-based answers to the questions your GP didn't have time for. A community of people who understand what it means to feel like your biology has been working against you — and are figuring it out together. Every Thursday at 8 pm UK time, I host a live Q&A. Bring your labs, your questions, your confusion. Nothing is too basic, and nothing is too complex. Sessions are recorded if you can't attend live. The Classroom will have structured modules on methylation fundamentals, supplement protocols, and fertility, with more added regularly. One thing before you do anything else Go to the Introductions category and answer this single question: What is your MTHFR variant, and what is the one question you most want answered? That's it. One question. I read every introduction personally and respond to each one. You're not joining a database. You're joining a conversation that could genuinely change how you understand your own health. Welcome. Jean-Marc Sobczyk, MD - The Methylation Doctor

New comment Jun 6

Kerryn Beal

Jun 4 •

Introduction

Checking in from Australia

I have MTHFR, thermolabile type c.665C>T (aka: C677T) heterogeneous and COMT c.472G>A and Ehlers Danlos Syndrome Classical Type. My current homocysteine levels are 11, ESR is 7, B12 is 173, folate 25, ferritin 348. I had an iron infusion about mid last year as it was very low. Honestly I’ve felt on edge ever since and now my levels are extremely high. I am at home recovering from ALIF surgery on my L4/5 after a workplace injury. Surgery was on January however I am still quite swollen. I have also acquired synovitis in the joints of my feet and toes due to my changed gait. I am inflamed and miserable. I am incredibly conscious with my food and I eat a well balanced plant based diet with a minimum of 30 different kinds of plants per week. I have removed all fortified folate from my diet. There is a strong history of alzheimers and heart disease in my family. I have been telling my doctors that I feel brain fog is getting worse and am now at the point where I feel like I don’t retain new information well despite being previously well educated with 2 degrees. In addition to this my watch keeps telling me that my heart rate is spiking and my hrv drops as low as 31 overnight. I am really hoping you can help. What supplements should I take and in what order? I am committed to my health however my GP is no help whatsoever and looks to be in worse health than I am! It is very difficult to find medical professionals to help. Most don’t seem to take this seriously.

New comment 23h ago