I have MTHFR, thermolabile type c.665C>T (aka: C677T) heterogeneous and COMT c.472G>A and Ehlers Danlos Syndrome Classical Type. My current homocysteine levels are 11, ESR is 7, B12 is 173, folate 25, ferritin 348. I had an iron infusion about mid last year as it was very low. Honestly I’ve felt on edge ever since and now my levels are extremely high. I am at home recovering from ALIF surgery on my L4/5 after a workplace injury. Surgery was on January however I am still quite swollen. I have also acquired synovitis in the joints of my feet and toes due to my changed gait. I am inflamed and miserable. I am incredibly conscious with my food and I eat a well balanced plant based diet with a minimum of 30 different kinds of plants per week. I have removed all fortified folate from my diet. There is a strong history of alzheimers and heart disease in my family. I have been telling my doctors that I feel brain fog is getting worse and am now at the point where I feel like I don’t retain new information well despite being previously well educated with 2 degrees. In addition to this my watch keeps telling me that my heart rate is spiking and my hrv drops as low as 31 overnight. I am really hoping you can help. What supplements should I take and in what order? I am committed to my health however my GP is no help whatsoever and looks to be in worse health than I am! It is very difficult to find medical professionals to help. Most don’t seem to take this seriously.

Hello! My variants are COMT rs4680 Val158Met Met/Met MTHFR r1801133 677C>T GA MTHFR r1801131 1298A>C TT

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Hello, thank you for sharing information about this topic. In Spain, people have no idea that this genetic mutation exists and that it can affect you so much in the long run. Doctors never test your homocysteine levels, and if you finally manage to convince one to order it in your bloodwork, they don't know what to do with the results afterwards. It’s unbelievable!! I believe in preventive medicine... I've suffered from migraines since I was 20, and my mother was diagnosed with cognitive decline 10 years ago. Ever since then, my search for answers began... and in the end, I had to diagnose the genetic mutation myself, researching and studying on my own. That's how I found you on Instagram and later on Skool. I have finally managed to get a hematologist to order the genetic test; I had it done yesterday, Tuesday, and I will have the results soon. I am already supplementing and managed to bring my homocysteine down from 53 to 30... but I still have a way to go. Thank you for all the valuable content you provide on this blog. Best regards.

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