Mar 17 (edited) • Start Here
📌 START HERE — Read This First
Free to join, including the weekly live Q&A, with optional premium membership for Q&A recordings and the MTHFR Clinician’s Guide.
You got an MTHFR result. Then what?
For most people, that moment goes one of two ways.
Your doctor glanced at it and said, "It's not clinically significant." Or you fell down a rabbit hole of contradictory websites, Facebook groups, and supplement protocols that left you more confused than when you started.
Neither of those should happen. That's exactly why this community exists.
I'm Jean-Marc — an integrative physician, 25 years in clinical practice and probably the only doctor you'll meet who gets genuinely excited about methylation genetics.
I’m a GMC-registered GP (GMC 6148690) with a special interest in methylation, seeing patients in person at Hooke London, Mayfair, and online worldwide.
I created The Methylation Hub because the gap between what the science tells us and what patients actually receive is one of modern medicine's most unnecessary failures. You deserve better than a shrug or a supplement shopping list.
This is what you'll find here
Clinical depth without the jargon. Evidence-based answers to the questions your GP didn't have time for. A community of people who understand what it means to feel like your biology has been working against you — and are figuring it out together.
Every Thursday at 8 pm UK time, I host a live Q&A. Bring your labs, your questions, your confusion. Nothing is too basic, and nothing is too complex. Recordings are available to Premium members.
The Classroom already holds The Archive (135 answers), the Fertility course and the MTHFR Clinician's Guide, with more added regularly.
One thing before you do anything else
Go to the Introductions category and answer this single question:
What is your MTHFR variant, and what is the one question you most want answered?
That's it. One question. I read every introduction personally and respond to each one.
You're not joining a database. You're joining a conversation that could genuinely change how you understand your own health.
Welcome.
Jean-Marc Sobczyk, MD - The Methylation Doctor
Your first 3 steps
Step 1: Classroom → The Archive. Search your question (135 answers, graded A–D).
Step 2: Introductions. Share your variant and your one question.
Step 3: Live Q&A every Thursday at 8 pm UK (see the Calendar).
Education, not medical advice. Everything here is educational. I am not your treating physician, and nothing here creates a doctor–patient relationship. Keep working with your own doctor before changing supplements, medication or tests. If symptoms are urgent, contact your doctor or emergency services.
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📌 START HERE — Read This First
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Make sense of your MTHFR result: 135 free answers, weekly live Q&A and courses from Dr Jean-Marc Sobczyk, MD. Education, not medical advice.
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