Got a solid question from a member:
“If I’m on TRT year-round, does that mean I can run AC262 longer?”
Let’s break this down in a logical way.
First — this is not medical advice. SARMs are not approved for human use. This is strictly an educational discussion around how hormones behave on paper and in lab work.
🔬 The Core Concept
If someone is on TRT year-round, their baseline testosterone level is being maintained externally.
That means suppression isn’t the same concern it would be for someone who is natural.
But here’s where most people get confused…
AC262 (like other selective androgen receptor modulators) binds to androgen receptors in muscle tissue. When those receptors are occupied, more circulating testosterone may show up as free testosterone on labs.
That does NOT automatically mean testosterone production increased.
It means hormone dynamics shifted.
Big difference.
⚠️ Where Problems Actually Happen
The issue usually isn’t total testosterone.
It’s what happens downstream.
Higher free testosterone can convert into:
• DHT
• Estrogen
• Prolactin shifts
And when guys start “feeling off,” they guess.
They assume:
- “It must be estrogen.”
- “It must be low test.”
- “I need an AI.”
Without labs, that’s just gambling.
And gambling with hormones stacks problems fast.
🧪 The Only Thing That Actually Tells the Truth: Labs.
Before. During. After.
Not feelings.
Not Reddit threads.
Not bro science.
Bloodwork tells you:
- Liver markers
- Lipids
- Total test
- Free test
- Estradiol
- DHT
- Prolactin
Without that data, you’re just reacting emotionally.
🧠 The Bigger Lesson
TRT doesn’t make you immune to side effects.
It just changes the variables.
Some people report running AC262 long-term without noticeable lab issues — but the key word is lab-verified.
Small problems start small.
Unchecked problems compound.
If you’re going to experiment with anything in the hormone world, the standard isn’t “Do I feel okay?”
The standard is “What do the labs say?”
👇 Let’s Open This Up
For those of you on TRT:
• Have you noticed changes in free test on labs when adding other compounds?
• What markers surprised you the most?
• Have you ever misdiagnosed your own side effects before getting labs?
Drop your experience below. Let’s keep this data-driven and useful for the group.
No guessing. No fear-mongering. No hype.
Just real discussion around real numbers.