15d (edited) • Mitochondria
Per Dr. Seeds _ Methylene Blue is not reliable measure of damaged mitochondria
Can you provide your feedback on the below... it is Dr. Seeds feedback on using methylene blue as an indicator for function status of Mitochondria.
*** Dr. Seeds Feedback -
Short answer: No. Methylene blue is not a safe or reliable non-medical way to check liver or kidney function.
Here’s a clear explanation without getting technical or giving instructions.
Why methylene blue does not work as a liver/kidney test
1. It’s not a diagnostic marker
Methylene blue is a dye and redox-active compound. Changes in urine color after exposure do not reflect how well your liver or kidneys are working.
  • Blue or green urine ≠ good or bad kidney function
  • Faster or slower color change ≠ liver performance
Those changes mainly reflect:
  • How the dye is processed chemically
  • Hydration status
  • Gut absorption
  • Individual metabolism
Not organ health.
2. The body handles it in multiple ways
Methylene blue:
  • Is partially metabolized in the liver
  • Is partially excreted by the kidneys
  • Is chemically reduced to leucomethylene blue (colorless)
Because of this, you cannot isolate liver vs kidney function based on what you see.
Too many variables = no meaningful conclusion.
3. Color changes are misleading
Urine color after exposure can change due to:
  • Dose size
  • Timing
  • Gut absorption
  • Gut bacteria
  • Hydration
  • Other foods, dyes, or supplements
This makes it uninterpretable outside a controlled medical setting.
Historical / medical context (important distinction)
In the past, methylene blue was used by doctors for very specific purposes, such as:
  • Certain lab-based kidney flow studies (obsolete now)
  • Specialized surgical or imaging contexts
⚠️ These were:
  • Controlled
  • Measured
  • Clinically supervisedNot self-tests.
Modern medicine does not use methylene blue to assess routine liver or kidney function.
Safety note (important)
Using substances to “test” organs on your own can be risky because:
  • It may interact with medications or conditions
  • It can cause side effects
  • It can give false reassurance or false alarm
Self-experimentation with dyes or chemicals is not advised.
Non-medical ways people observe liver/kidney stress (not tests)
These do not diagnose, but can raise awareness:
Kidney-related functional signals
  • Persistent foamy urine
  • Swelling in ankles or around eyes
  • Very dark urine despite hydration
  • Low urine output
Liver-related functional signals
  • Poor tolerance to fatty foods
  • Persistent nausea
  • Yellowing of eyes or skin (needs medical attention)
  • Easy fatigue after meals
If these appear, the correct step is medical evaluation, not DIY testing.
Bottom line
  • ❌ Methylene blue cannot check liver or kidney function
  • ❌ Urine color changes are not meaningful data
  • ❌ It should not be used as a self-test
  • ✅ Organ function requires proper clinical tests
If your interest is energy, mitochondria, or metabolism, methylene blue is sometimes discussed in research — but that is a completely different topic from organ function testing.
1
4 comments
Taylor S
2
Per Dr. Seeds _ Methylene Blue is not reliable measure of damaged mitochondria
Castore: Built to Adapt
skool.com/castore-built-to-adapt-7414
Where science meets results. Learn peptides, training, recovery & more. No ego, no fluff—just smarter bodies, better minds, built to adapt.
Leaderboard (30-day)
Powered by