10d • General discussion
Worse before better
Has anyone experienced feeling worse before better on peptides—specifically new joint discomfort—before seeing improvement?
I’m heading into week 4 and, while I understand that tissue remodeling, nervous system sensitization, hormonal disruption, and load mismatch during healing can all be part of the process, I’m noticing new shoulder joint pain and mild elbow joint discomfort, in addition to not really feeling improvement yet in my original injured areas (knee/hip).
Current/recent stack:
- BPC-157 / TB-500
- Tesa/IPA
- Reta
- Glutathione
- GHK-Cu
- Paused ashwagandha + cortisol-lowering supplements
No acute swelling, redness, or sharp pain—more of a stiff, achy, “jammed” joint feeling.
For those who’ve run similar protocols:
- Is this something you experienced early on?
- Did things eventually turn around, and if so, around what timeframe?
- Or did this signal the need to pause, adjust load, or simplify the stack?
Not looking for medical advice—just real-world experiences. Appreciate any insight
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Worse before better
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