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Built With // MS

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Life is Built through movement, nutrition, purpose, and community. Show up daily, build better habits, and discover what you're capable of.

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18 contributions to BioOptimization Collective
30 Day Bio-Opt Challenge
Why Are You Here? Let's Start With Your Goal. Welcome to the Challenge! If you're here, chances are you're looking to improve something about your health. Maybe it's fat loss. Maybe it's muscle. Maybe you're recovering from an injury. Maybe you just want more energy. No matter where you're starting from, you're in the right place. One thing I want everyone to understand from Day 1... There isn't a magic peptide. Peptides don't replace hard work. They don't replace good nutrition. They don't replace sleep. They don't replace consistency. They're simply one tool that may support the work you're already putting in. That's what this community is about. We're here to learn from the research, share experiences respectfully, and help each other become healthier, not chase shortcuts. If you could improve ONE thing over the next 90 days, what would it be? - Lose body fat - Build muscle - Heal an injury - More energy - Better sleep - Better hormones - Healthy aging - Better focus - Something else? Tell us below.
1 like • 8d
Focus/Build lean muscle/lose body fat.
1 like • 7d
@Michelle Heaton and @Sean K curious what you guys do for diet? As Travis always talks about it's the full system including peptides. I always love seeing what other areas people are working on.
Stop Asking, "What Peptide Should I Take?"
This is probably the most common question I get... "What's the best peptide?" My answer is always the same... It depends on your goal. The best peptide for someone trying to lose 50 pounds isn't the best peptide for someone recovering from an injury. The best peptide for improving skin isn't the best peptide for building lean muscle. Here's the mistake I see people make all the time... They pick a peptide first and hope it solves their problem. Instead, define the problem first. Your goal determines the strategy. The strategy determines the tools. And peptides are just one of those tools. Before you ever think about peptides... Ask yourself these five questions: ✅ Am I eating enough protein? ✅ Am I strength training consistently? ✅ Am I sleeping at least 7 hours? ✅ Am I drinking enough water? ✅ Am I walking every day? If you answered "no" to most of these, start there. Those habits create the foundation that any peptide strategy builds on. Write your health goal using this sentence: "By this time next year, I want to __________ because __________." Be specific. The more specific your goal, the easier it is for this community to help you get there. One thing you'll learn about me... I'm never going to tell you a peptide is the answer. I'm going to help you build the habits first, because those are what create lasting results. When your nutrition, training, sleep, and recovery are dialed in, that's when we can have a conversation about whether a peptide might fit your goals. Let's build the foundation first.
1 like • 7d
Always comes back to the outcome you want. Great reminder!
Can Retatrutide Change Your Emotions?
Can Retatrutide Change Your Emotions? Here's What the Research Says. This question a lot lately: "Does Retatrutide suppress your emotions?" The honest answer is... it might for some people, but there isn't solid scientific evidence showing that it directly suppresses emotions. What researchers do know is that Retatrutide affects the brain's reward system. That's one reason many people notice less food noise, fewer cravings, and less interest in things like alcohol or other impulsive behaviors. For some people, that feels freeing. For others, it can feel like they're not as excited about things they used to enjoy. It's also important to remember that if you're losing weight quickly, eating in a large calorie deficit, sleeping poorly, or going through hormone changes, those factors can affect your mood too. The key takeaway is this: Just because you feel emotionally different doesn't automatically mean Retatrutide is the cause. Look at the whole picture before jumping to conclusions. Now I'm curious... If you've taken Retatrutide, have you noticed any changes in your mood, emotions, or motivation? I'd love to hear your experience. Let's have a respectful conversation so everyone can learn from real-world experiences.
0 likes • 9d
@Travis Dickey aside from it's effectiveness, which clearly it works as a weight-loss compound) what is your honest take on is Retatrutide actually healthy? And/or what should people be doing, if anything, before exploring Retatrutide for themselves?
Poll Results On Longevity Peptides
Mots-C received the most votes. Then #2 was Epitalon. #3 GHK-CU and #4 SS-31. Most people accept aging as inevitable. The science increasingly does not. What we call aging is a measurable cascade of cellular events. Mitochondrial decline. Telomere shortening. Collagen breakdown. Chronic inflammation that never fully resolves. These are not mysteries. They are addressable biological processes. And four compounds in the current research literature are targeting each one of them directly. MOTS-c — Your Mitochondria Have a Longevity Signal. Here Is How to Restore It. Identified in 2015 by researchers at USC and published in Cell, MOTS-c is encoded directly in mitochondrial DNA and activates AMPK — the same metabolic switch triggered by fasting and exercise. Published research shows improved insulin sensitivity, enhanced fat oxidation, and increased endurance in study models. A 2019 study confirmed MOTS-c levels decline significantly with age in humans, correlating directly with metabolic dysfunction and reduced physical capacity. This is not a synthetic compound mimicking a natural process. It is the natural process itself, restored. Epitalon — The Only Compound Shown to Activate Telomerase in Human Cells Every cell division shortens your telomeres. When they get short enough cells stop dividing and begin secreting inflammatory signals that accelerate aging in surrounding tissue. That process is called cellular senescence and it is one of the primary drivers of age-related disease. Epitalon, developed by Dr. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, has demonstrated telomerase activation in human somatic cells in peer-reviewed research published in Neoplasma. It has also shown restoration of melatonin rhythms, improved immune function, and in long-term studies a statistically significant extension of lifespan. Over 35 years of research and more than 100 published studies back this compound. That is not a claim. That is a track record.
1 like • 26d
@Victor Ortega 100%. I felt the same way on SS31. I just had to make a decision my self what to focus on and I went inflammation reduction and metabolic health focus first with the stack I’m on. Might go back to SS31… maybe during winter when it’s grey and cold :)
0 likes • 26d
@Victor Ortega mitochondria right now 😂
The 5 Most Promising Peptides for Longevity and Performance in 2026
The world of peptides is evolving fast. Every week, new compounds are being discussed in biohacking groups, longevity communities, and performance circles. Some are overhyped. Some are poorly understood. And a few may genuinely change the future of human health and aging. After reviewing the latest discussions and research trends, these are the five peptides that have captured the most attention from scientists, clinicians, and biohackers alike. 1. Retatrutide: The Next Generation Fat Loss Peptide Many experts believe Retatrutide could eventually outperform both Semaglutide and Tirzepatide. Why? Because it targets three metabolic pathways instead of one. Potential benefits include: Significant fat loss Improved insulin sensitivity Better metabolic health Reduced cardiovascular risk This may become one of the most important metabolic therapies of the next decade. 2. MOTS-c: The Exercise Mimetic What if your cells could act as if they had exercised? MOTS-c is a mitochondrial peptide that appears to improve energy production, metabolic flexibility, and physical performance. Researchers are studying its role in: • Healthy aging • Metabolic health • Mitochondrial function • Exercise performance For longevity enthusiasts, this is one of the most exciting peptides currently being explored. 3. Humanin: Protecting Your Cells From Aging Humanin is another mitochondrial-derived peptide that may help protect cells from age-related decline. Potential benefits include: Neuroprotection Reduced inflammation Improved cellular resilience Support for healthy aging As we learn more about mitochondria and longevity, Humanin continues to gain attention. 4. SS-31 (Elamipretide): Mitochondrial Repair Most age-related diseases involve mitochondrial dysfunction. SS-31 is designed to target and improve mitochondrial efficiency. Researchers are investigating its potential for: • Heart health • Energy production • Muscle performance • Healthy aging Of all the peptides currently being studied, SS-31 may have some of the strongest scientific backing.
1 like • Jun 24
What a list! The problem is picking what stack to b use together as there is seemingly a peptide for most things you could want.
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Adam Koller
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@adam-koller-3821
Changed my life with MS. You can change yours too no matter what you're building with. Start the 7-Day Reset: BuiltWithMS.com

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