Tomorrow, AMP kicks off their BEST sale of the year and they absolutely crushed it. Research USE ONLY Here's the breakdown: ✅ 10% OFF SITEWIDE (automatic) ✅ Code DEREK15 stacks for another 15% OFF ✅ Loyalty members get an EXTRA 5% OFF Do the math: You're looking at up to 30% OFF Stackable if you're a loyalty member. This beats their Black Friday sale and runs December 12th through Christmas Day. 🎁 NEW 3D CASE UNBOXING AMP sent me a care package with their brand new 3D case (now available for purchase) and I did a full unboxing below 👇 The case quality is legit - this is what proper peptide storage should look like. SHOP HERE: https://ameanopeptides.com/?ref=Derek15 Don't sleep on this one. 30% off stackable discounts don't come around often. Drop a 🎄 if you're grabbing anything from this sale! P.S. - Sale starts tomorrow (Dec 12th) so set your reminders. Stock up for Q1 research while these prices are live.

Hey everyone! I just rolled out a feature that I think is going to make your life a LOT easier when shopping these sales. 🔍 How It Works You'll now see an orange percentage indicator next to prices on PeptidePrice.store. Click it, and you'll get a complete breakdown of exactly how the math works on stacked discounts. 📊 Real Example Check out this AOD-9604 listing from AMP Peptides: - Original Price: $35.00 - Holiday Sale (-10%): $35.00 × 0.90 = $31.50 (saves $3.50) - Code derek15 (-15%): $31.50 × 0.85 = $26.77 (saves $4.73) - Final Price: $26.77 - Total Savings: $8.23 (24% off!) The breakdown shows you step-by-step how each discount applies and compounds, so there's no more guessing about whether codes stack or if you're just getting the sitewide sale. 💡 Why This Matters I know there's been confusion about: - "Does my code stack with the sale?" - "Am I getting the best deal?" - "How did they calculate this?" Now it's 100% transparent. If discounts are stackable, you'll see the ⚡ indicator and the full math. If it's just a sitewide sale, you'll see that too. Demo video: https://vimeo.com/1145957694?share=copy&fl=sv&fe=ci Try it yourself: https://peptideprice.store Let me know what you think! Any feedback is welcome 🙏

Alright, so Lilly dropped their TRIUMPH-4 Phase 3 data yesterday for retatrutide. 28.7% weight loss. 71 pounds average. At 68 weeks. If you've been paying attention to triple agonists, this shouldn't be surprising. The Phase 2 data already showed us where this was headed. But now we have the Phase 3 confirmation. Here's what happened: 445 people with obesity and knee osteoarthritis. Split into three groups - 9mg retatrutide, 12mg retatrutide, and placebo. The 12mg group lost an average of 71.2 pounds. That's 28.7% of their starting weight. Compare that to tirzepatide's ~21% in Phase 3. That's 8 percentage points higher. The glucagon agonism makes the difference - you're not just suppressing appetite, you're ramping up energy expenditure and fat oxidation. Why triple agonists hit different: Retatrutide is GIP + GLP-1 + Glucagon. You already know GLP-1 from semaglutide. You know the dual combo from tirzepatide. The glucagon piece is what pushes this into a different category. - GLP-1 = appetite control - GIP = metabolic optimization - Glucagon = fat-burning accelerator You're hitting all three mechanisms simultaneously. The inflammation piece is wild: This trial was designed for knee osteoarthritis, not just weight loss. The pain results were massive: - 76% reduction in pain scores - 74% improvement in physical function - 12% of people completely pain-free by week 68 But here's what's interesting - this wasn't just about losing weight and reducing load on the joints. Retatrutide crushed inflammatory markers across the board. hsCRP dropped significantly. Triglycerides down. Blood pressure down 14 mmHg. Each component has anti-inflammatory effects. GLP-1 reduces pro-inflammatory cytokines. GIP has protective effects on bone and cartilage. Glucagon ramps up fat burning, and less adipose tissue means less inflammatory signaling. You're not just taking pressure off the knee - you're turning down systemic inflammation that's driving the pain in the first place.

Hey everyone - there's been some stuff I've been dying to fix. The whole reason PeptidePrice exists is because I wanted to build THE all-in-one tool that makes it stupid easy for every researcher to make informed decisions. You're about to see some big changes coming: 1. Stackable Discounts (finally fixing this) I've seen the confusion with Valor's sale and Peptira's pricing before - their sites auto-markdown prices (like $100 → $80), then your coupon code applies on top (80 → $72). Right now that's not super clear on my site. Don't worry, I have a fix for this and it's coming soon... 2. No More "Ghost" Sales I'm actively staying on top of retailers now. Not launching ANY sales or products on the site until I personally verify they're live and functional. Too many times I've had owners say "hey this is live" → I check and it's out of stock or coupons don't work. Not a good look for me, so even if sales are delayed a bit, I want the best experience for you all. 3. Price Tracking is LIVE (retailers, I see you 👀) The backend price tracking tool is running. If I catch a price hike right before these sales, I'm calling it out and advertising based on what prices were just days ago. So far since Black Friday, it's been solid. PSA to all retailers: 30% off isn't 30% off when you hike prices up 20% first. Not acceptable. Run your business how you want, but I'm gonna keep it real. 4. Shipping Updates Shipping costs and policies have been changing like crazy. I haven't been keeping it 100% up to date - that's changing NOW. Adding this to my daily updates with some advanced features to make it more visible on the site. 5. Content Strategy Shift Content will still come out, but I'm trying to be more impactful with every post. This might mean less overall volume, but I want to break down the full picture so you can make informed decisions as researchers. Quality over quantity. 6. 2026... 👀 I'll keep the bonus features quiet for now, but you're not ready for what's coming. PeptidePrice will continue to level up. We don't stop.

Everyone's been asking me about Jay Campbell's recent podcast where he claimed GLP-1s are about to be completely shut down in the research and compounding space. His prediction? Eli Lilly is coming with lawsuits, Trump cut a deal, and by 2026 you won't be able to get sema or tirz anywhere except through prescription at their new "discounted" prices ($199-$299/month). Here's my issue: Jay spent half that podcast selling a $1,200/month follastin product. So when someone's pushing expensive products while saying affordable options of proven peptides are disappearing... 🤔 That said... Eli Lilly just hit a $1 TRILLION market cap. A monopoly on GLP-1s makes perfect business sense. And we saw what happened with SS-31—these shutdowns CAN happen fast. Speaking of SS-31, Ben and I covered that rapid shutdown in our podcast. If you want to see how quickly things can change in this space, check it out: 🎥 YouTube: https://youtu.be/oCjljZn2ZoU 🎧 Spotify: https://open.spotify.com/episode/5KkQvR4xvgYKD1hLG7vKV7 📝 Show Notes: https://open.substack.com/pub/beyondthevial/p/beyond-the-vial-episode-2-black-friday My take? I don't think it'll be as dramatic as Jay claims, but I also wouldn't completely ignore the warning. Should you stock up? Maybe. Should you panic? No. I break down the whole situation, the political angle, what this could mean for research vendors, and what you should actually do about it. Read the full article here: https://open.substack.com/pub/derekpruski/p/will-glp-1s-disappear-from-the-research?r=4jq1x8&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true ⚠️ Full disclosure: This is 100% my opinion and speculation. I don't have insider info. Just giving you my honest take based on what I'm seeing.