HowSS-31 and MOTS-C fit into the process One of the biggest mistakes people make when starting something like Redatrutide is assuming appetite suppression alone is the solution. In reality, appetite control is only part of the equation. What your cells do with energy matters just as much. This is where mitochondrial optimization comes in. Step 1: Understanding the Foundation From Dr. Sears’ work, one principle comes up over and over again: If the mitochondria aren’t working well, the system downstream doesn’t respond optimally. If someone already feels: - Low energy - Easily fatigued - Metabolically “stuck” - Inflamed or stressed at the cellular level Jumping straight into aggressive appetite suppression can backfire. Calories go down, but energy, recovery, and metabolic flexibility go down with it. That’s why SS-31 is often used first. Phase One: Redatruride + SS-31 Optimizing the engine before changing fuel intake SS-31 works at the mitochondrial membrane level. It’s studied for helping mitochondria produce energy more efficiently and reducing oxidative stress. Think of it as improving how well the engine runs. When SS-31 is introduced before or alongside Redatrutide: - Cells handle lower calorie intake better - Energy production is more efficient - Fatigue risk is lower - The metabolic system feels more stable This phase is especially helpful for people who know their body isn’t optimized yet or who have a history of crashing when dieting. Conceptually: SS-31 helps prepare the system so Redatrutide doesn’t feel like a shock. Phase Two: Redatrutide + MOTS-C Using fuel more intelligently once appetite is controlled Once appetite and food noise are under control with Redatrutide and mitochondrial stress is reduced, MOTS-C becomes a powerful addition. MOTS-C is a mitochondrial-derived peptide studied for: - Improving glucose utilization - Supporting insulin sensitivity - Enhancing metabolic flexibility - Helping the body shift toward fat utilization

Glutathione doesn’t get talked about enough, but it’s one of those things that quietly does a lot of heavy lifting in the body. It’s often called the body’s “master antioxidant,” and that’s not marketing; it’s because glutathione helps protect cells from stress, supports the liver’s detox pathways, and helps the immune system function the way it’s supposed to. When glutathione levels are high, the body just tends to handle stress better. When they’re low, things feel harder than they should. Levels naturally decline with age, stress, poor sleep, illness, alcohol, medications, and environmental toxins. That’s why people often look into glutathione when they’re feeling run down, inflamed, or like recovery just isn’t what it used to be. This isn’t a stimulant. It’s not a weight-loss product. You don’t usually “feel” it like you do with caffeine or a pre-workout. It’s more foundational. It supports the systems that keep everything else running smoothly, especially the liver and the cells. I always like to remind people that glutathione is about protection and resilience, not quick fixes. Over time, supporting antioxidant capacity can make a real difference in how the body handles stress, toxins, and recovery. As always, education matters. Understanding what something actually does helps you decide whether it fits your goals, rather than just chasing the next trend. Educational discussion only. Not medical advice.

This is one of those small details that actually matters more than people think. When it comes to reconstituting peptides, the water temperature matters, but probably not for the reason most people assume. Based on compounding pharmacy standards and peptide handling best practices, room-temperature bacteriostatic water is preferred for reconstitution. Peptides dissolve more evenly at room temperature, and it reduces the chance of clumping or stressing the peptide structure during mixing. Using refrigerated water isn’t dangerous, but it can slow dissolution and sometimes leads people to shake or over-agitate the vial, which is far more damaging than the water temperature itself. Cold water doesn’t add any extra protection during reconstitution. What actually protects peptide integrity is how gently you handle it: - Inject the water slowly down the side of the vial - Never shake — only swirl gently - Use bacteriostatic water, not saline - Refrigerate the peptide after it’s fully reconstituted That last part is important. Cold storage matters after reconstitution, not during the mixing step. So the simple rule I follow and teach is this: Reconstitute with room-temperature bacteriostatic water, handle the peptide gently, then store it refrigerated. It’s not about overthinking it — it’s about avoiding unnecessary stress on something that’s already fragile. Education first. Technique matters. Educational discussion only. Not medical advice.

I’ve been on reta a few months very slowly titrating up so haven’t seen result due in part, to the dose and lifestyle right now. Food noise is still there, but I noticed some differences here in there. As of months ago, I had some insulin resistance likely to lifestyle and estrogen imbalance. For overall weight management and to help with fatigue and low energy, would you stack with mots-,c NAD+ or something else?

“My three peptides for someone over 40, who just wants to feel better. Here’s the truth… It doesn’t matter if you’re a man or a woman, once you hit 40, the same systems start slowing down: Energy, recovery, metabolism, sleep, mood, and inflammation. So if I had to give a universal starter foundation, these are the three that make the biggest impact for most people. Now, if you’ve had recent bloodwork done, you could dial in your top 3 peptides. 1. NAD — energy, mood, and cellular function 2. BPC-157 — inflammation, joints, gut, healing 3. CJC-1295 + Ipamorelin — sleep, recovery, confidence, fat loss And here’s what most people don’t realize… Men and women feel these peptides differently. Men notice faster recovery, better strength, and fat loss around the stomach. Women notice better sleep, mood stability, skin/hair benefits, and fat loss around the hips/thighs. Same peptides, different outcomes, because the hormone environment is different. But the top three don’t change. Everyone over 40 needs better energy, better repair, and a better recovery period. Now I want to hear from you: If you could fix ONE thing in your body right now — just one — what would it be? Energy? Mood? Sleep? Recovery? Inflammation? Confidence? Drop it in the comments. This is where the real education starts, because your answers tell me exactly how to lead this group. — Travis