This week our challenge was 1 min max effort on the Airdyne for calories. 💪🥵

We get this question a lot, which is exactly why we put together a simple list of the research supplies we actually use and trust, instead of having people guess. When it comes to needles and syringes, the goal is accuracy, consistency, and reliable delivery — not what’s smallest or trendiest. That’s why: - Smaller syringes = better accuracy for small doses - And why I generally prefer a ½” 29g needle over a 5/16” 31g The slightly longer length gives more margin for consistent subQ delivery across different body types and injection sites. The shorter 31g needles can work, especially if someone is very lean, but they’re more technique-dependent and easier to be too shallow with. Comfort-wise, most people don’t notice a meaningful difference. All of the supplies we recommend are basic, no-nonsense tools we personally purchase through Amazon because they’re easy to source, consistently available, and clearly spec’d. Nothing fancy. Nothing gimmicky. Just reliable equipment that supports clean, precise research practices. Everything shared is for research and educational purposes only. The goal is to remove confusion, save time, and help people follow best practices. Start simple. Stay organized. Be precise. That’s how real research is done. Link for Reconstitution Solution: https://a.co/d/041SVcEm Link for Alcohol Prep Pads: https://a.co/d/0fX2kyaL Link for 1mL, 29 Gauge, 1/2 inch Syringes: Note you can also find a purchase different size syringes depending on your application: https://a.co/d/0c8tbJvb

Let’s Clear This Up. This comes up a lot, so I want to reframe an important point. When someone tells me they’re “microdosing” retatrutide because they’re splitting a 2 mg weekly dose into four 500 mcg injections, that is not microdosing. That’s called split dosing, and there’s a big difference. What Microdosing Actually Means In pharmacology, microdosing has a specific definition: Less than 1/100th of the dose that produces a measurable pharmacological effect. At that level: - You don’t meaningfully activate receptors - You don’t reach therapeutic blood levels - You don’t get real metabolic or appetite effects So when we’re talking about drugs like retatrutide, true microdosing does not work. What Most People Are Really Doing: Split Dosing If your total weekly dose stays the same, but you divide it into smaller, more frequent injections, that’s split dosing. Example: - 2 mg once per week - 1 mg twice per week - 500 mcg four times per week All of these add up to 2 mg per week. The total weekly dose hasn’t changed — only how it’s delivered. Why Split Dosing Can Make Sense Retatrutide has a long elimination half-life of about 6 days. That means: - After 6 days, roughly half of the injected amount is still in your system - Each new dose stacks on top of what hasn’t been eliminated yet Over time, this creates a rolling average concentration in the bloodstream. Eventually, you reach what’s called a steady state, where the amount you’re injecting equals the amount your body is eliminating. This usually takes about 4–5 half-lives, regardless of how often you inject. What matters most is total weekly dose, not injection frequency. Why Microdosing Retatrutide Doesn’t Work True microdosing never allows you to: - Reach steady state - Achieve sufficient receptor activation - Maintain concentrations high enough to produce results GLP-based drugs have a threshold effect. If you don’t reach that threshold, nothing meaningful happens.

This calculator is a research planning tool. https://peptide-prep-buddy.lovable.app/ It helps you: - Measure correctly - Stay consistent - Plan how long your research materials will last - Avoid mistakes and waste It does not give medical advice or tell you how to use anything on people. It only helps with math and planning. How to Think About Research Peptides Imagine you are doing a science project with: - A container of powder - Water to mix it - A measuring tool If you do not measure the same way each time. - Results are inconsistent - Material gets wasted - Planning becomes difficult This calculator helps you measure the same way every time. Step-by-Step: What to Enter 1. Vial Amount (mg) This is how much research material is in the vial. Examples: - 5 mg - 10 mg Enter the number exactly as it appears on the vial label. This tells the calculator how much total material you are working with. 2. Water Added (mL) This is how much liquid you added to mix the vial. Examples: - 1 mL - 2 mL Adding more water does not add more peptide. It only spreads the same amount over more liquid. 3. Target Amount (mcg) This is the size of one measured portion. Examples: - 100 mcg - 250 mcg Smaller amounts mean more portions per vial. Larger amounts mean fewer portions per vial. This step controls how long the vial will last. 4. Syringe Type This tells the calculator how your measuring tool is marked. Options: - U-100 (most common) - U-40 (less common) - mL only (liquid markings, no units) Always choose the option that matches the syringe you are using. If this is wrong, the math will be wrong. 5. Syringe Size (Capacity) This is how much liquid the syringe can hold. Common sizes: - 0.3 mL - 0.5 mL - 1.0 mL This helps prevent trying to draw more liquid than the syringe can hold. What the Calculator Shows You Concentration This tells you how strong the liquid is after mixing.

Six hours of sleep isn’t ideal—but pretending it’s eight doesn’t make it so. If your schedule is fixed, the smartest move isn’t chasing supplements or sedatives. It’s engineering depth, timing, and recovery efficiency inside the window you actually have. That means: - Falling asleep faster - Spending a higher percentage of the night in slow-wave sleep - Making sure GH and melatonin are peaking inside your sleep window—not outside it Peptides don’t replace sleep. They increase the return on each hour when the duration is capped. This Is About Compression, Not Hacking: The mistake people make is trying to force sleep: - More pills - More sedation - More unconsciousness That usually backfires by flattening deep sleep and fragmenting REM. The approach outlined here does the opposite: - Calm the nervous system without sedation - Bias sleep toward delta waves - Amplify the recovery signals that already occur during deep sleep - Align circadian timing so those signals happen when you’re actually asleep You’re not extending the night. You're compressing more restoration into it. One More Time, Plainly: If you’re stuck at ~6 hours, the hierarchy is: 1. Onset speed – Don’t waste 45 minutes lying awake 2. Slow-wave density – More deep sleep per hour 3. GH efficiency – Bigger recovery signal during SWS 4. Circadian timing – Right sleep at the right biological time Everything in the stack maps to one of those levers. Don’t Skip the Boring Stuff: No peptide overrides these: - Same bed and wake time, even on weekends - Dark room, cool temperature, zero light leaks - Caffeine out by early afternoon - Alcohol nowhere near bedtime - Last real meal 3–4 hours before sleep If those are broken, peptides just make an expensive mess. Bottom Line: If eight hours isn’t happening, stop pretending it will. Build a protocol that: - Gets you asleep faster - Pushes you deeper - Makes your GH pulses count - Keeps your circadian rhythm honest