Some peptides sting on injection. This is usually due to acidic reconstitution, histamine release, or technique, not because anything is “wrong” with the peptide. When needed, topical numbing agents can make injections more tolerable, especially for peptides known to burn on entry. Numbing Options: Lidocaine creams (2–5%) - Most effective - Apply a thin layer 15–30 minutes before - Must be entirely removed before injecting Lidocaine or benzocaine wipes - Faster onset (5–10 minutes) - Milder effect - Useful for light sting or quick prep Combo creams (lidocaine + prilocaine) - Deeper numbing - Slower onset - Use sparingly and remove completely How to Use Properly: 1. Apply to intact skin only 2. Wait for the numbing to take effect 3. Remove all residue 4. Clean with alcohol 5. Let alcohol fully dry 6. Inject slowly Never inject through numbing cream or any residual product. Other Ways to Reduce Sting (Often Enough on Their Own) - Inject slowly - Use smaller gauge needles - Rotate sites - Let the alcohol dry completely - Warm the syringe slightly in your hand Good technique solves most sting issues without numbing. Bottom Line: Injection discomfort is a chemistry and technique issue, not a peptide problem. Numbing creams and wipes are optional tools; use them correctly, and only when needed. All content is for educational and research discussion only.