Stability Study of Semaglutide Over a 12-Month Period
Theorized hypothetical: You've given yourself your recently reconstituted GLP shot the Thursday before visiting your Great-Aunt Mable 2000 miles away for two weeks over the holidays. You inadvertently leave your GLP sitting out, unrefrigerated, on the counter, while you're gone. Your anxiety heightens once you realize you left it out. You think to yourself, "Well, that's money down the drain!" Fear not! The study below researches stability and purity of Semaglutide (GLP1) after one year thanks to my vendor partner at Good Life Peptides. https://www.goodlifepeptides.com Code: KRISTINAMARIE Abstract: This study evaluated the stability of Semaglutide when stored under three different conditionsāroom temperature (average 23 °C), refrigeration (average 4 °C), and freezing (average -17 °C)āover a 12- month period. The Semaglutide used was obtained from Good Life Peptides (https://goodlifepeptides.com/) (base vial concentration: 1.99 mg, 99.7% purity). Parameters assessed included quantitative recovery and purity, determined using high-performance liquid chromatography (HPLC). The results demonstrated that Semaglutide maintained stability across all conditions, with minor variations in both quantity and purity. Materials and Methods: Sample Preparation- Source: Semaglutide base vial (1.99 mg, 99.7% purity) purchased from Good Life Peptides. Distribution: Nine vials were divided into three storage groups (n = 3 per condition): o Room Temperature (average 23 °C) o Refrigerator (average 4 °C) o Freezer (average -17 °C) Storage Equipment: Standard residential refrigerator and freezer unit. Handling- At the conclusion of the 12-month storage period, all vials were removed from their respective storage conditions and brought to room temperature. Samples were then shipped under ambient conditions via UPS 2-Day Air to Prime Analytical Labs for testing. Analytical Testing: Testing Facility: Prime Analytical Labs (https://primeanalyticallab.com/)