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Exploring Peptides Community
9.8k members • Free
102 contributions to Research Peptide Community
2d •
Tirz
I received my first order from step one and started Tirz this afternoon. I wanted to see what everyone’s results has been with step one Tirz and if any side effects. I have only used compound Tirz through my doctor office so just trying to get feed back 😊
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1 like • 17h
@Alyssa Golden i started out on step one, 2.5mg tirz, yep!
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0 likes • 16h
@Tammy W thanks so much! 🎊
Dec '25 •
Switching glp2-glp3 advice
My cousin and I were looking into R-GLP3. We're currently involved with T-GLP2. Anyone who's been here, can you please give as much detail as possible? Because when you switch do you start back at the bottom? Up by 2.5 and such? I heard it helps tremendously with inflammation. Experiences with research you've done on it?
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1 like • 9d
Typical Transition Strategy (High-Level) Phase 1: Stabilize tirzepatide Stay on a stable tirzepatide dose Make sure side effects are minimal before changing anything Phase 2: Introduce retatrutide at a very low dose Retatrutide is started at a micro / introductory dose Tirzepatide is kept the same initially This phase is about tolerance, not weight loss ⏱️ Usually 1–2 weeks Phase 3: Begin decreasing tirzepatide Tirzepatide is reduced stepwise Retatrutide is increased slowly, one step at a time Only one change per adjustment period Either ↓ tirzepatide or ↑ retatrutide — not both simultaneously ⏱️ Adjustments typically spaced 2–4 weeks apart Phase 4: Full transition Tirzepatide is fully discontinued Retatrutide reaches its maintenance range Appetite suppression and metabolic effects usually feel stronger at this stage ⏱️ Full transition often takes 6–10 weeks ⚠️ Signs you’re moving too fast If any of these happen, titration should pause: Persistent nausea or vomiting Severe fatigue or “flat” feeling Dizziness/lightheadedness Food aversion or inability to eat Resting heart rate noticeably higher than normal 🧠 Why slow matters (especially with reta) Retatrutide’s glucagon activity can increase energy expenditure That same mechanism can worsen: Anxiety Insomnia Fatigue Slow titration lets your CNS and GI system adapt 📋 Strongly recommended labs before or during transition Especially since you mentioned fatigue & brain fog earlier: CMP (electrolytes, liver) B12 Iron / ferritin TSH + free T3/T4 A1C or fasting insulin Bottom line ✔️ Slow ✔️ One adjustment at a time ✔️ No full-dose overlap ✔️ Expect 6–10 weeks for a clean transition
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Nov '25 •
Healing & Pain
Well, RS had surgery on Friday, so its been one whole week. Previously, RS had breast cancer, followed by a lumpectomy. This time on an MRI, they noticed an issue with 2 of my RS's lymph nodes. After removing them, they noticed they were NOT CANCER!!!! My RS allso received 2 sacral nerve block injections as well. My question to you is this... im still in soo much pain, and I've been told the whole "take Tylebol" for your pain. What else can my RS take for healing and pain?? Thanks so very much for your help!
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1 like • 22d
@Kevin Kinchen I really appreciate you. Thanks!!
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1 like • 22d
@Kevin Kinchen , I hear you on that one!
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Jun '25 •
FAVORITE PEP...
Just curious... write below why you like that pep the best!
Poll
53 members have voted
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0 likes • Nov '25
@Diane Hinkle what side effects? Cardiac?
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1 like • 29d
@Josh Tipton tirz is always the top contender! Thank you for your input! I didn't list reta because I honestly didn't think of it when I did the poll, lol. I just put peps that came to mind right away. No other reason...youre definitely right though! Reta is all the rage!!
Dec '25 •
Weekend Update and Pre-Holiday Sale
🎄 Exclusive Holiday Sale: Extra 20% Off In-Stock GLPs + 10% Off Everything!🎄 The holidays are here, and we're spreading extra cheer with an exciting limited-time offer! While we're busy restocking after our record-breaking Thanksgiving sale, we're thrilled to give you a special deal on our in-stock GLPs. Now through December 22nd, enjoy: - An extra 20% off all in-stock GLPs - Plus 10% off your entire order (site-wide!) Simply use code HOLIDAY at checkout to unlock these savings. Fresh Arrivals Alert! We've just added multiple new products to the shop—be sure to browse and discover what's new. Important Holiday Shipping Schedule To ensure your orders arrive smoothly and to give our team a well-deserved break: - Holiday GLP Sale ends December 22nd - We will be closed December 23rd – 26th(Checkout will be disabled) - Orders placed starting December 27th will begin shipping on January 2nd, 2026 (we'll be open for orders starting December 27th) - Mark your calendar: Our New Year's Site-Wide Sale runs December 27th, 2025 – January 4th, 2026! Details to come...... Thank you for your continued support—it means the world to us. We wish you and your family a joyful, safe, and wonderful holiday season!
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4 likes • Dec '25
So 30% off?! Wow, thank you! 🥰
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1 like • Dec '25
@Josh Tipton sure did!! Woo hoo!!
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@jennifer-dietrich-9262
5'3" 45 yrs old
HW 298, SW 255(9/24/24),
CW 108, GW115
Active 3h ago
Joined May 30, 2025
Wisconsin
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