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12 contributions to Biohacking and Longevity group
Ever feel like your fat loss progress just… disappears?
You dial everything in. You see changes.Then suddenly, it rebounds. That is not random. It is metabolic adaptation. In this new article, we break down why fat rebound happens, how adaptive thermogenesis works, and why AOD-9604 continues to be discussed in fat metabolism and lipolysis research. If you are interested in the science behind disappearing progress and adipose signaling pathways, this one dives deep. https://open.substack.com/pub/edparker92/p/progress-that-disappears-aod-9604?r=6xjs6j&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true 🔥 25% OFF Launch SpecialCode FEB25 auto applied at checkout for the next week. Read the full breakdown here 👇
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Ever feel like your metabolism is just… broken? AOD-9604 Discussion
You’re eating less. Training harder. Doing everything “right.”Yet fat loss stalls — and when calories go up, weight rebounds fast. That’s not failure. That’s metabolic adaptation. When calories stay low for too long:• Metabolic rate can decline• Thyroid signaling may shift• Lipolysis can become less efficient• Fat cells may become primed to store again In this new article, we break down the science behind why your metabolism feels damaged — and why AOD-9604 continues to show up in fat metabolism research conversations. If you’re interested in the real biology behind plateaus and fat regain, this is worth the read. https://open.substack.com/pub/edparker92/p/why-my-metabolism-feels-broken-aod?r=6xjs6j&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true 🔥 25% OFF Launch SpecialCode: FEB25 (auto-applied for the next week) #AOD9604 #MetabolicAdaptation #FatLossScience #OrionPeptides
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Why does fat seem to return immediately after dieting?
When calories drop, the body adapts. Metabolic rate can decline. Thyroid signaling may shift. Lipolysis can slow. Fat cells may even become more efficient at storing energy once calories increase again. This is where AOD-9604 enters research conversations. Studied as a modified fragment of growth hormone, AOD-9604 has been explored for its role in lipolytic signaling and fat metabolism pathways — without the full spectrum activity of GH itself. In this article, we break down:• Why fat regain happens• What metabolic adaptation really means• Why AOD-9604 continues to attract research attention If you’re interested in the science behind fat signaling, this one’s worth reading. https://open.substack.com/pub/edparker92/p/fat-that-returns-immediately-aod?r=6xjs6j&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true #AOD9604 #FatLossResearch #MetabolicScience #Lipolysis
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Why Does My Sleep Cycle Feel Off? GH Discussions
Disrupted sleep isn’t just about staying up late — it’s deeply connected to hormonal rhythms, especially growth hormone (GH). Scientists are finding that GH release during deep sleep plays a critical role in tissue repair, metabolism, and overall recovery. In our latest research-focused article, we explore: - How GH influences sleep architecture and circadian rhythm - Why your body may not be getting enough deep sleep - Investigational peptides are used in lab studies to study GH and sleep patterns If you’re interested in cutting-edge research and want to understand the science behind sleep disruptions, this is a must-read. https://open.substack.com/pub/edparker92/p/why-my-sleep-cycle-feels-off-gh-research?r=6xjs6j&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true #SleepResearch #GrowthHormone #GH #PeptideResearch #CircadianRhythm #OrionPeptides
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Feeling Physically Drained Too Often? The Science Might Be Deeper Than You Think.
Energy regulation, recovery signaling, and growth hormone pathways remain major areas of focus in modern laboratory research. Our newest article explores how CJC-1295 + Ipamorelin are being studied for their role in GH signaling, metabolic pathways, and recovery-related mechanisms. If you’re interested in the science behind peptide research and how investigators examine biological fatigue at the molecular level, this is a must-read. https://open.substack.com/pub/edparker92/p/why-you-might-feel-physically-drained?r=6xjs6j&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true 💡 Researchers can explore high-purity compounds at Orion Peptides and enjoy 15% OFF with code WELCOME15. For laboratory research use only. Not for human consumption. #PeptideResearch #LaboratoryScience #CJC1295 #Ipamorelin #GrowthHormoneResearch #OrionPeptides #ScientificResearch
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Ed Parker
3
43points to level up
@ed-parker-8165
I’m Ed Parker—a peptide researcher sharing clear, no‑BS insights on what works and why.

Active 12h ago
Joined Jan 8, 2026