Nov 2 • Peptide Tips
Why You Might Gain Weight (or Stall) When Starting Tesamorelin 🤔
Let's answer this question because it comes up on the daily.
Just started tesamorelin and the scale went UP? Or maybe it's not budging at all? Don't panic - this is actually pretty common and here's why:
What's Happening Behind The Scenes
Tesamorelin is a growth hormone-releasing hormone (GHRH) that triggers your body to produce more natural GH. When you first start, several things happen simultaneously:
1. Water Retention & Glycogen Storage
- Increased GH levels boost glycogen storage in muscles
- Each gram of glycogen holds 3-4 grams of water
- This can add 2-5 lbs on the scale in the first few weeks
- This is GOOD weight - it's stored energy, not fat
2. Muscle Protein Synthesis Kicks In
- GH stimulates muscle tissue development
- Muscle is denser than fat (weighs more per volume)
- You might be losing fat while gaining muscle simultaneously
- The scale doesn't show the composition change
3. Increased Appetite Initially
- Some people experience hunger changes early on
- Your metabolism is ramping up and needs fuel
- This usually stabilizes after 2-4 weeks
The Real Timeline
Weeks 1-3: Scale might go up or stall (water/glycogen/muscle) Weeks 4-8: This is when fat loss typically becomes visible Weeks 8-12: Most people see significant body composition changes
What To Track Instead
✅ Progress photos (front, side, back)
✅ Body measurements (waist, hips, arms)
✅ How your clothes fit
✅ Energy levels and recovery
✅ Skin quality improvements
❌ Don't obsess over daily scale weight
Pro Tips
- Take measurements BEFORE you start
- Give it at least 8-12 weeks before judging results
- Stay consistent with dosing
- Keep protein intake high (supports muscle growth)
- Stay hydrated (helps with the water retention phase)
Bottom line: That initial weight gain or plateau is usually your body RESPONDING to the peptide, not failing. Trust the process and look at the bigger picture! 💪
Has anyone else experienced this? Drop your timeline below! 👇
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Why You Might Gain Weight (or Stall) When Starting Tesamorelin 🤔
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