This Is Why I Preach COAs And Batch Numbers On Everything

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You guys know by now — I'm a broken record about certificates of analysis and lot numbers. Today I want to show you exactly why.

A situation just popped up where somebody was trying to verify a batch of semaglutide from Ion. The batch was old — back from September — before Ion joined the price tool. Before they came on, I made it a requirement that they batch test everything and apply lot numbers to their COAs. Before that, there were a bunch of people promoting them, but old batches didn't have any of those numbers.

So this customer reaches out trying to verify their semaglutide. The problem? The number they had on the vial was from the manufacturer — not from Ion. There was no matching lot number to trace back to a specific COA.

Luckily, I knew Ion had tested that batch. I went through and contacted Shay directly to track down the matching COA because I knew it existed — it was just hard to find without a proper lot number linking everything together.

And good thing we found it.

The sample was overfilled by over 10mg.

Let that sink in for a second. You think you're researching with a 10mg vial of semaglutide, but you're actually working with 20+ mg. You reconstitute it the same way, draw up what you think is your research amount — and you're getting MORE THAN DOUBLE what you planned for.

This is one of the biggest reasons people get wrecked with side effects from their research peptides and have no idea why. Nausea out of nowhere. Feeling terrible after a dose that was fine last time. Sides that don't match what the dose should be producing. A lot of the time, it's not the peptide — it's that nobody checked whether the vial was overfilled or underfilled. And without a COA tied to a specific lot number, you have no way of knowing.

Overfill means you're dosing higher than you think. Underfill means you're dosing lower and wondering why nothing is working. Both are problems. Both are avoidable if you verify your COAs.

This is your reminder:

Always verify your COAs. Always check the actual peptide content — not just the purity percentage, but the net peptide weight. Always make sure the lot number on your vial matches the lot number on the COA. If there's no lot number, that's a red flag.

The last image is what Ion's new COAs look like. We've come a very long way. Proper lot numbers, proper batch testing, everything traceable. Thank you to Ion for trusting the process and putting in the work to make things better and more transparent for the end researcher.

I will have another post about Ion's testing, but they also plan to add sterility and heavy metals.

Code Derek @ Ion Peptides

This is what the standard should look like across the industry. No excuses.

Research Use Only Not For Human Consumption

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