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Dec '25 (edited) • Peptide Tips
How NAD+ Actually Works: The Molecule That Powers Your Entire Body 🔋
NAD+ is an electron shuttle that carries energy from your food to your cellular power plants (mitochondria).
Think of it as a delivery truck that:
- Picks up electrons from broken-down food
- Delivers them to the energy production line
- Gets recycled and goes back for more
- Repeats this thousands of times per day
The Energy Production Process
STEP 1: Food Breakdown
- Carbs → Glucose
- Fats → Fatty acids
- Protein → Amino acids
STEP 2: Krebs Cycle (Where NAD+ Shines)
- NAD+ grabs electrons 3 times per cycle
- Becomes NADH (loaded with energy)
- Without NAD+, this cycle STOPS
STEP 3: Electron Transport Chain (The Big Payoff)
- NADH delivers electrons
- Powers ATP production (your actual energy)
- Makes ~30 ATP per glucose molecule
- NADH converts back to NAD+ (recycled!)
Total from 1 glucose: ~32 ATP molecules
90% of that energy requires NAD+ to work
The NAD+ Cycle
NAD+ doesn't get used up - it gets recycled in a continuous loop:
- NAD+ (empty) picks up electrons in Krebs Cycle
- Becomes NADH (full)
- Delivers electrons to Electron Transport Chain
- Powers ATP production
- Becomes NAD+ again (empty)
- Repeats thousands of times per day
The Problem: NAD+ Decline
By age 40: 50% less NAD+ than at age 20 By age 60: Only 25% remains
What this means:
- Same food eaten
- Same calories consumed
- WAY less ATP produced
- You feel exhausted for "no reason"
It's like running the same energy production line with half the delivery trucks. Everything slows down.
Why Supplementation Works
When you take NMN or NR:
- Increases NAD+ pool (more delivery trucks)
- Krebs Cycle runs efficiently (no bottleneck)
- More NADH produced and delivered
- More ATP from the same food
- Better fat burning (NAD+ needed for beta-oxidation too)
Result: You're not adding energy - you're fixing the machinery that produces it.
Beyond Energy Production
NAD+ also powers:
- DNA repair (PARP enzymes)
- Longevity genes (Sirtuins)
- Sleep/wake cycle regulation
- Immune function
Low NAD+ means all of these suffer too.
The Bottom Line
NAD+ is the electron delivery system that enables your body to convert food into ATP.
Without enough NAD+, your energy production crashes - even if you're eating perfectly.
Supplementing with NMN/NR restores the delivery fleet to youthful levels.
Same food → More NAD+ → More ATP → More energy
Want the full deep dive?
Read the complete breakdown with all the biochemistry here:
Questions? Drop them below 👇
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How NAD+ Actually Works: The Molecule That Powers Your Entire Body 🔋
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