I want to preface this by saying I’m generally not a huge fan of traditional EAAs. While they’re interesting from a research standpoint, what actually moves the needle is still the basics: consistent weight training and hitting your daily protein targets. If those aren’t dialed in, EAAs are just noise.
In most cases, simply adding more high-quality protein will do far more for results than any EAA stack ever will. The fundamentals matter first.
That said, a lot of community members have been asking about them, so let’s take an objective look and break down the EAA formulations from Solution and Atomik Labs—what they’re doing well, where they differ, and where they realistically fit (if at all).
Let's Start Simple: What Are Essential Amino Acids (EAAs)?
The body needs 20 amino acids to function. Think of them as building blocks — they build muscle, repair tissue, produce hormones, support the immune system, and keep the brain working properly.
Of those 20, 9 are "essential" — meaning the body CANNOT make them on its own. They must come from external sources.
This blend contains all 9 of those essential aminos in a ready-to-use liquid form.
🔬 This product is sold for research purposes only and is not intended for human consumption.
🧪 What's In This Blend (And What Each One Does)
Let me walk through each amino acid in plain English, starting with the highest dosed:
Histidine — 45mg/mL (the star of this blend)
This is the most heavily dosed amino in the formula, and for good reason.
- Converts into histamine in the body, which regulates immune response, stomach acid, and inflammation
- Acts as a powerful antioxidant — helps neutralize free radicals
- Supports gut health and digestion
- Plays a role in maintaining the myelin sheath (the protective coating around nerves)
- Research links it to reduced inflammation markers and improved metabolic function
- Key focus in studies on chronic inflammation, gut health, and metabolic stress — particularly in caloric deficit models
Threonine — 35mg/mL
This one is underrated and often overlooked.
- Critical for collagen and elastin production (skin, joints, connective tissue)
- Supports the gut lining — helps maintain the mucus barrier that protects the intestines
- Plays a role in immune function by supporting antibody production
- Helps with fat metabolism in the liver
- Studies on significant weight loss and GLP-1 receptor agonist use highlight the importance of supporting skin elasticity and gut barrier integrity — threonine is directly involved in both
Lysine — 35mg/mL
One of the more well-known aminos, and for good reason.
- Essential for collagen synthesis (works alongside threonine)
- Helps the body absorb calcium more efficiently
- Supports immune function — commonly studied in relation to HSV management
- Plays a role in carnitine production, which helps convert fatty acids into energy
- Frequently studied for its dual role in lean tissue preservation and fat metabolism — two processes that often compete during caloric restriction
Methionine — 25mg/mL
This is the methylation and detox amino.
- Precursor to glutathione — the body's master antioxidant
- Supports liver detoxification pathways
- Critical for methylation — a process involved in DNA repair, hormone regulation, and neurotransmitter production
- Helps with natural creatine production
- Key subject in studies on hepatic function, detoxification capacity, and methylation efficiency — especially relevant when other compounds are being studied concurrently
Phenylalanine — 20mg/mL
This is the mood and cognition amino.
- Converts into tyrosine, which then becomes dopamine, norepinephrine, and epinephrine
- Supports mental clarity, motivation, and alertness
- Research suggests potential benefits for pain modulation through enhanced endorphin activity
- Studies on cognitive function and neurotransmitter production frequently examine phenylalanine as a rate-limiting precursor in the dopamine synthesis pathway
Leucine — 10mg/mL
The most well-known BCAA and the anabolic signaling trigger.
- Directly activates mTOR — the pathway that signals muscle protein synthesis
- Most studied amino for MPS (muscle protein synthesis)
- Even small amounts act as a signaling molecule to initiate repair processes
- Think of it as the ignition key, not the gas tank — small doses are sufficient to activate the mTOR pathway
Valine — 5mg/mL
The quiet workhorse of the BCAAs.
- Supports energy production during physical stress
- Helps with muscle tissue repair
- Works alongside leucine and isoleucine as a team
Isoleucine — 5mg/mL
The other supporting BCAA.
- Helps regulate blood sugar by improving glucose uptake into cells
- Supports energy during physical activity
- Aids in hemoglobin production (oxygen transport)
Tryptophan — 2mg/mL (lowest dose, intentionally)
The recovery and mood amino — dosed conservatively for a reason.
- Precursor to serotonin (mood regulation) and melatonin (sleep/recovery)
- Supports calm and recovery processes
- Low dose supports these pathways without causing sedation
- The conservative dosing is intentional — enough to feed serotonin and melatonin pathways without introducing unwanted sedative effects in study models
🤔 Why a Liquid Form Instead of Oral EAA Powder?
Great question. Here's the key difference:
Oral EAAs (powder/capsules):
- Processed through the digestive system
- Broken down by stomach acid and liver (first-pass metabolism)
- Bioavailability varies widely — estimates range from 20-50% absorption
Liquid EAAs (subcutaneous administration):
- Bypass digestion entirely
- Delivered directly into tissue
- Near 100% bioavailability
- Lower total dose needed for equivalent or superior effect
So while 182mg per mL sounds small compared to 10g of oral EAA powder, the actual utilization rate is dramatically higher with direct administration.
Research Administration Overview (NOT MEDICAL ADVICE, RUO)
- Route: Subcutaneous (subQ) administration
- Typical research dose range: 0.5mL, 1-2x per day. Start low and build your way up.
- Storage: Room temperature — do NOT refrigerate (per manufacturer guidelines)
- No reconstitution needed — supplied in ready-to-use liquid form
For those already familiar with peptide administration, the process is identical — same syringes, same subcutaneous sites.
🎯 Research Applications — Where This Blend Is Most Relevant
Based on the composition, this blend is particularly relevant for research in the following areas:
- Caloric deficit models — when caloric intake is restricted, amino acid availability from food drops. This provides targeted EAA support directly.
- GLP-1 receptor agonist studies — appetite suppression often leads to reduced protein/amino acid intake. This fills those gaps without requiring increased food volume.
- Recovery protocols — post-exercise, post-procedure, or general tissue repair research.
- GI absorption studies — for models where oral absorption is compromised or inefficient, subcutaneous administration bypasses the issue entirely.
- Skin, hair, and connective tissue research — the histidine/threonine/lysine stack in this blend is specifically relevant to these structural proteins.
If you're eating enough protein and weight training regularly, this blend is not something you need to add in. For whatever reason, if protein goals weren't able to get hit and there was no other protein source available, that's when I turned to EAAs.
🔬 For research use only. Not intended for human consumption.
Questions? Drop them below. 👇