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14d (edited) • Peptide Tips
Coming Off a GLP-1? Don't Make This Mistake 🚨
If you're thinking about stopping your GLP-1 for any reason—whether it's cost, you've hit your goal, or something else—please don't quit cold turkey. You've probably heard the claim that you will regain all the weight you lost when stopping a GLP-1, and it's simply not true.
Here's why this matters and how to do it right.
What's Actually Happening in Your Body
GLP-1 peptides work by mimicking a natural hormone that tells your brain "you're full." Over time at higher doses, your body adapts to that level of signaling. When you suddenly remove it, your brain essentially goes from hearing a loud "stop eating" signal to near silence overnight.
The result? Your hunger doesn't just return—it often comes back with a vengeance. This is why so many people regain weight rapidly after stopping abruptly.
The Smart Approach: Titrate Down
The same way you titrated up, titrate back down.
Every 2-4 weeks, reduce your dose by roughly half OR drop by 1-2 mg (depending on what you're using). This gives your body time to recalibrate at each level.
Example timeline:
- Week 1-2: Full dose → Half dose
- Week 3-4: Adjust to the new hunger level
- Week 5-6: Half again or drop another 1-2 mg
- Continue until you're at the lowest dose, then stop
Why This Works
At each step down, you'll feel a slight increase in hunger—but it's manageable. Your brain gets time to readjust to lower levels of satiety signaling gradually, rather than being thrown into the deep end.
Think of it like slowly turning down the volume instead of hitting mute.
Stack the Odds in Your Favor
As you taper, support your body with lifestyle factors:
- Protein first – Aim for 30-40g per meal. Protein is the most satiating macronutrient
- Fiber up – Vegetables, legumes, and whole grains keep you fuller longer
- Whole foods over processed – Less hyperpalatable foods = fewer cravings
- Stay hydrated – Thirst often masquerades as hunger
These habits matter MORE as your GLP-1 dose decreases. Build them now while you still have the appetite suppression working in your favor.
The Bottom Line
Everyone I've talked to who tapered down properly will tell you the same thing: it's so much easier than quitting cold turkey.
You put in the work to get here. Don't sabotage your results by rushing the exit. Take your time, trust the process, and give your body the chance to adapt.
Questions about your specific situation? Drop them below 👇
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Coming Off a GLP-1? Don't Make This Mistake 🚨
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