Apr 10 • General discussion
Tesamorelin: When I Increased My Dose… the Scale Jumped 8 lbs 😳
Personal Experience Update:
I know we already did a deep dive on Tesamorelin, so I wanted to share my personal experience with it so far, because this was a good reminder that protocols don’t always play out the same way for everyone.
I started at 250mcg and tolerated it really well the first week. Since everything seemed good, I increased it to 500mcg.
Within that week I noticed pretty significant water retention and the scale went up almost 8 pounds. Now logically I knew there was no possible way to gain that much fat that fast — but seeing the number jump like that definitely messes with your head a little.
I decided to stick it out another week to see if my body would adjust… but the water retention didn’t change.
So I dropped back down to 250mcg, which is where I’m currently at, and the water weight has already started coming back down again.
It was honestly surprising how just a small dose increase made such a big difference. Some people’s bodies are just more sensitive to certain peptides, and I think I’m probably one of those people.
My protocol originally had me titrating up to 1mg by June 16, but this experience reminded me that more isn’t always better.
Sometimes the smartest move is listening to your body and adjusting, even if that means staying at a lower dose or moving up more slowly.
Curious if anyone else here has had a similar experience with Tesamorelin — especially when increasing doses. Did your body eventually adjust or did lowering the dose help?
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Tesamorelin: When I Increased My Dose… the Scale Jumped 8 lbs 😳
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