Saffron shows promise for autism spectrum disorder and beyond

Saffron is one of the most exciting natural compounds I've come across in the last decade. A comprehensive review in the Journal of Ethnopharmacology explores saffron's potential applications for autism spectrum disorder and related challenges like anxiety, sleep disturbances, and cognitive difficulties.

Saffron's bioactive compounds (crocins, crocetin, picrocrocin, and safranal) work through multiple pathways simultaneously: they reduce neuroinflammation, activate the body's natural antioxidant defenses, and help restore balance between calming and excitatory brain signals.

This multi-target approach is particularly relevant for autism spectrum disorder, where inflammation in the nervous system, oxidative stress, and neurotransmitter imbalances often occur together. What makes saffron especially compelling is its versatility beyond autism. Clinical research demonstrates that it improves mood, supports better sleep quality, and promotes relaxation and stress relief. The review emphasizes that saffron could serve as a complementary therapy, though more rigorous clinical trials are needed to establish optimal dosing and long-term safety.

For families navigating autism spectrum disorder or anyone interested in natural approaches to cognitive and emotional health, saffron represents a promising avenue worth discussing with your healthcare provider.

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