A 5-agonist is a single peptide designed to activate five metabolic receptors at the same time.
TARGETS
GLP-1
GIP
Glucagon
Amylin
Calcitonin
WHAT EACH ONE DOES
GLP-1
Reduces appetite and slows digestion
GIP
Improves insulin response and nutrient handling
Glucagon
Increases calorie burn and energy output
Amylin
Enhances fullness and reduces meal size
Calcitonin
Extends satiety and supports metabolic regulation
OVERALL EFFECT
Lower food intake
Longer-lasting fullness
Higher energy expenditure
Better glucose control
WHAT IT IS
A next-generation multi-agonist peptide built to combine appetite control, satiety, and calorie burning into one compound
CURRENT STATUS
Still in development and not commercially available
SIMPLE SUMMARY
One peptide
Five pathways
Full metabolic control in a single mechanism