Livagen is the "liver" name on most bioregulator lists. It gets talked about as a liver and anti-aging peptide, but the research behind it is small and mostly done in a dish. Here's the simple version. WHAT IT IS Livagen is a short lab-made peptide of four amino acids: lysine, glutamic acid, aspartic acid, and alanine (written Lys-Glu-Asp-Ala, or KEDA). It comes from the Khavinson bioregulator program in St. Petersburg, Russia, the same group behind Epitalon, Cortagen, and Cardiogen. It was designed as a small synthetic version of the idea behind a liver extract from calves that the same group studied. WHAT PEOPLE USE IT FOR • Liver support ideas in the longevity community • "Aging cells" and gene-activity conversations • Stacking talk with other Khavinson bioregulators WHAT THE RESEARCH ACTUALLY SHOWS • Human cells in a dish: the best-known study (Khavinson et al., 2002) took white blood cells from older people and exposed them to Livagen in the lab. The authors reported that tightly packed "switched off" parts of the DNA loosened up and some genes became more active. They read that as reversing an age-related change in the cells. • Animal tissue: rat liver and other tissue samples grown in a dish responded to Livagen in a way the authors called tissue-specific. • Animal liver models: a 2020 review from the same group describes Livagen helping liver function and immune markers in animals with induced liver damage. • Humans: there is no published, controlled human trial of Livagen taken as a treatment, and nothing is registered on ClinicalTrials.gov. Evidence level: Very Early. Cell and animal studies, nearly all from one research lineage, with no independent replication and no human outcome data. COMMON QUESTIONS Is Livagen a liver medication? No. It is not approved in the US for any liver condition, and it has not been tested against real liver disease in people. Is it the same as Epitalon? No. They look similar on paper but the amino acids are different: Epitalon is AEDG and Livagen is KEDA.