Activity
Mon
Wed
Fri
Sun
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
What is this?
Less
More
2 contributions to Castore: Built to Adapt
Dependence from Adderall, dopamine question
Hi All, Have a friend who tried to go cold turkey from A 15 year dependence on adderall. I’ve had him focused on his diet, exercise and day to day habits. Since removing adderall, he is experiencing differing levels of anxiety (heart palpitations, racing thoughts, etc). My thoughts are his dopamine receptors and levels are shot. Any thoughts on peptides that could help reset? Anyone else know of anyone like this and approaches others took? Thanks, Nate
1 like • 3d
Thanks for the time Anthony. Love the things highlighted above
Sleep Issues/Feeling Wired: Looking for some feedback
I’m 38 and have always been active. I originally got into peptides using the Wolverine stack for a running-related knee injury. About 10 weeks ago I started a pretty aggressive cut while trying to maintain/build muscle. I started at 215 lbs / 24% BF by DEXA and am currently 190 lbs, estimating around 15% BF. I lift 5x/week for about an hour and run 3x/week. For most of the cut I was eating very clean, in a deficit, and very low carb. This week I increased carbs significantly and started carb cycling. Main issue: My sleep fell apart about 3 weeks ago. I used to get 6–7 hours. Now I have trouble falling asleep and/or wake up completely awake between 2–3 a.m. and struggle to get much more than 5 hours. What’s strange is I don’t feel tired at all—I feel wired and have tons of energy. Mentally and physically I actually feel great, and brain fog I used to have is gone. But obviously 5 hours of sleep isn't sustainable. I go to bed around 9 and wake at 4:15 to train. I also use blue-light glasses at night. Current stack: - CJC/Ipa – 400 mcg AM + PM (tried AM only, no improvement in sleep) - KLOW - Tirzepatide – 750 mcg 2x/week - SLU-PP-332 – 500 mcg 2x/day - 5-Amino-1MQ – 2 mg AM - Glutathione – 120 mg 3x/week - Urolithin A – daily - SS-31 – 5 mg/day (started today) - VIP – 200 mcg/day (started today) - IGF-1 LR3 – 100 mcg/day (started today) - Enclomiphene – 12.5 mg, 5x/week (started today) I was previously on retatrutide but switched to tirzepatide after my resting HR increased about 9 bpm. Since switching, HR is back to baseline. I’ve tried DSIP for the sleep issue without much success. Two of my worst nights were actually on it. I also have Epitalon and Pinealon that I purchased based on their potential effects on circadian rhythm/sleep, but haven't started them. I was planning to wait until after the SS-31 and IGF-1 LR3 cycles. One other piece that may be relevant is testosterone. About 4 years ago I was in the 200s. Two months ago I tested at 640 total / 15.2 free, which surprised me. Yesterday I tested again at 384 total, SHBG 24, LH 6.4 (free wasn't tested). Previous LH was 4.7. I've also been using ashwagandha, zinc, boron and tongkat ali for the last couple months.
1 like • 4d
Glutathione probably has you wired. Remove it for a couple weeks. When I first started glutathione it would wreck my sleep because I was taking too late in the day. I moved glutathione up to first thing in the morning (nasal spray) and it went much better. Def notice glutathione was what was wrecking my sleep in my stack
1 like • 3d
@Kevin Andersen report back if it helps!
1-2 of 2
Nathan Eckstein
1
2 points to level up
@nathan-eckstein-7062
Excited to move away from a life of pharmaceuticals

Active 2d ago
Joined Jul 14, 2026
Powered by