@Mariam Als. Hi Mariam 🧡 Yes — if **DHEA-S has been persistently elevated for a long time**, including before carnivore, and it did not really change after a year low carb, I would not automatically blame the diet. Your thought process is reasonable in one sense: **DHEA-S is produced predominantly by the adrenal glands**, so an isolated elevation does make me think about the adrenal source more than the ovaries. But I would be careful with the phrase “nervous system issue,” because elevated DHEA-S by itself does **not** prove that stress or the nervous system is the cause. What matters is **how elevated it is, whether it is stable or rising, your age, your symptoms, and what the rest of the androgen picture looks like**. If testosterone and SHBG are normal and you do not have progressive signs like worsening facial hair, severe acne, scalp hair loss, voice deepening, increased muscle mass, menstrual disruption, or other signs of virilization, that is generally less concerning than a rapidly rising DHEA-S accompanied by obvious androgenic symptoms. Rapid progression or severe biochemical androgen excess is where endocrinology becomes more urgent. I would also want to know the **actual DHEA-S value, units, your lab's reference range, and your age**, because DHEA-S naturally declines with age and should be interpreted against an age-appropriate range. Different laboratories and assays can also give somewhat different results, so one isolated number is less useful than the trend. A few things I would want to rule through systematically: **1. PCOS or an adrenal-predominant androgen pattern** PCOS can involve elevated DHEA-S even when testosterone is not dramatically elevated, although the diagnosis is based on the whole clinical picture, not DHEA-S alone. Menstrual regularity, ovulation, acne, body-hair changes, ovarian findings and other hormones all matter. Since you mentioned insulin is now low and looking good, that is excellent metabolically, but it does not completely rule PCOS in or out.