Most of your favorite peptides probably have something to do with weight loss or body composition. That's part of why ARA-290 gets overlooked. It's ultimate purpose is for repair and anti-inflammation. It's a synthetic peptide derived from erythropoietin (EPO) but without the cardiovascular risks. They essentially isolated the repair components that help with neuroprotection and tissue-protection while getting rid of the part that stimulated red blood cell production. ARA-290 binds to something called the innate repair receptor (IRR). These receptors are formed and appear on the outside of localized areas where severe metabolic stress, low oxygen, or tissue injury exists. This is basically a receptor that can be targeted to create a shift in the local environment that may be pro-inflammatory and tissue-damaging and turn it around into a healing and tissue repair environment by reducing cytokine production and enhancing some tissue repair processes. If you read the Immune System course, cytokines are your immune system's inflammatory signaling molecules that are driving inflammation for various reasons throughout the body. In animals, they actually observed long-term relief after sciatic nerve injury, and that relief came FAST. In humans, they've looked at it for small fiber neuropathy. Small fiber neuropathy is the nerve damage that can cause burning, tingling, and pain. In the sarcoidosis group, it significantly helped with neuropathic and autonomic symptoms and 28-days of treatment was actually able to initiate regrowth of small nerve fibers in the cornea. The same thing happened in the type 2 diabetes patients, but they also had a better metabolic profile (so pay attention to that side of things if using). In all populations, there were really no significant adverse effects. From personal experience, I can tell you that within 4 days, my sciatic pain was almost completely gone. Before ARA-290, I was limping around half of the day. The reconstitution protocol is in the classroom over in the paid community as well because this one can be a bit tricky.

Not sure whats going on but the fatigue is real. Currently just started SS31, Semax & 5Amino. This feels like when I first started Reta. 🫩 as follows: Semax @ 500mcg Daily 5Amino @ 250mcg Daily SS 3x weekly @ 2mg KLOW 3x weekly @ 4mg Reta 1x weekly(titrated up to 4mg beginning of the month)

This is probably the most common question I'm seeing now. What's the best dosage? How often for MOTS-C? Over in the paid community ($10/month), I have the explanation for this broken down in the Consolidated Reconstitution, Dosage, and Cycle Lengths Course. I actually have the protocols written out for all of the peptides. This is how it's written in that course: Common Dosages - Injectable: MOTS-C protocols can vary quite a bit in terms of dosages and frequency. People do anywhere from 0.5 to 5mg per injection. Ultimately, I think that starting on the low end to assess individual response, then increasing over time if needed is the best way to do it. If you can respond well at 0.5 mg and get what you need out of it, great. You saved money. Timing - Injectable: Because this typically gives energy, best time to take it is in the morning or pre-workout. It can be done either daily, every other day, or 5 days on 2 days off. So basically, starting low to assess effects does 1 of 2 things: 1. Let's you find an effective dosage 2. Saves you money Typically though, if someone is looking for the energy that it gives, they do it daily as that's how long the energy lasts for them. If they're looking for exercise performance increases, they may only take it on the days before a workout. But if looking for the metabolic benefits, increased insulin sensitivity, etc. then typically only a few times a week can be sufficient. Also, people say that they keep seeing a lot of varied protocols out there for this one. Well, this protocol covers it all. This post also explains the reasoning / justification behind the various frequencies. Now back outside to keep pressure washing and I'll be back in a bit if there are any questions!

Hey everyone! I like to ask this question periodically as it helps me direct my focus. What is the most confusing thing to you right now? Where are you getting stuck? Let me know below!

I posted this over in the paid community, but want to make sure everyone over here understands this! If you've ever used AOD, ARA, or a few others, you may have noticed gelling or clumping. There are a few peptides where you may need a solvent other than BAC in order to get them to reconstitute properly. These liquids are NOT interchangeable with each other. They will need one or the other. Acetic Acid: This has a LOWER pH number. The pH of the solution is around 2.75-3. Compounds that may need this: AOD-9604 (almost always), HGH Frag 176-191 (this is basically AOD by the way), Kisspeptin (sometimes, not always). Tesamorelin, CJC-1295, Sermorelin should NOT need this if you're using Hospira branded BAC water. Phosphate Buffered Saline or Sodium Bicarbonate Solution: These have a HIGHER pH number. Depending on which one, the pH is around 7-8. Compounds that may need this: ARA-290 (almost always), Thymosin Alpha-1 (sometimes). If you use the reconstitution cheat sheets, I tell you the appropriate solutions to use. I have a vendor working on getting the sodium bicarbonate solution in stock currently. I feel like it's important for you to understand the pH differences to understand that you can't use AA for a PBS-requiring compound and vice versa or it will take the pH in the wrong direction and probably make things worse.