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Neanderthals Used Ancient Gloop as Antibacterial Medicine Relatives of modern humans may have created and used a sticky substance both as a glue and to treat their wounds, preempting modern medicine by as much as 200,000 years, a new study suggests. Researchers have known that Neanderthals used birch tar, a viscous substance derived from birchbark, to glue spear points onto handles in a process known as hafting. This substance has been found across Europe, and it served multiple purposes, including as some of history's oldest water sealant and Hubba Bubba. "Alongside these findings, there is also growing evidence of medicinal practices and the use of plants among Neanderthals, which is why we were interested in the use of birch tar in this context," explains Tjaark Siemssen, an archaeologist at the University of Cologne and Oxford University and the study's lead author. So in the recent study, researchers at the University of Cologne, the University of Oxford, and the University of Liège recreated this birch tar using the ingredients and processes that were possibly utilized by Neanderthals. Then, researchers at Cape Breton University in Nova Scotia, Canada, performed biological tests to confirm the tar's medicinal properties. "That is exactly what we proved. The substance Neanderthals made 200,000 years ago, we now know, also possesses antibacterial properties," says Matthias Bierenstiel, a professor of chemistry at Cape Breton University and study co-author. To recreate this deeply historical glue-medicine, the researchers collected bark from two types of (dead) birch trees widely documented during the Late Pleistocene, circa 129,000 to 11,700 years ago. They then used three tar extraction methods to turn the bark into a gooey, spreadable compound. The first method involves heating birchbark in a tin. This technique is inspired by the Mi'kmag nation, the Indigenous people of Nova Scotia, who for generations have used birch tar as a cornerstone of their traditional pharmacy.

Tattoos Affect Your Immune System in Ways We're Just Beginning to Understand From minimalist wrist designs to full sleeves, body art has become so common that it barely raises an eyebrow. But while the personal meaning of a tattoo may be obvious, the biological consequences are far less visible. Once tattoo ink enters the body, it does not stay put. Beneath the skin, tattoo pigments interact with the immune system in ways scientists are only just beginning to understand. Tattoos are generally considered safe, but growing scientific evidence suggests tattoo inks are not biologically inert. The key question is no longer whether tattoos introduce foreign substances into the body, but how toxic those substances might be and what that means for long term health Tattoo inks are complex chemical mixtures. They contain pigments that give color, liquid carriers that help distribute the ink, preservatives to prevent microbial growth, and small amounts of impurities. Many pigments currently in use were originally developed for industrial applications such as car paint, plastics, and printer toner, rather than for injection into human skin. Some inks contain trace amounts of heavy metals, including nickel, chromium, cobalt, and occasionally lead. Heavy metals can be toxic at certain levels and are well known for triggering allergic reactions and immune sensitivity. Tattoo inks can also contain organic compounds, including azo dyes and polycyclic aromatic hydrocarbons. Azo dyes are synthetic colorants widely used in textiles and plastics. Under certain conditions, such as prolonged exposure to sunlight or during laser tattoo removal, they can break down into aromatic amines. These chemicals have been linked to cancer and genetic damage in laboratory studies. Polycyclic aromatic hydrocarbons, often shortened to PAHs, are produced during the incomplete burning of organic material and are found in soot, vehicle exhaust, and charred food. Black tattoo inks, commonly made from carbon black, may contain these compounds, some of which are classified as carcinogenic.

I have added the Comprehensive Cardiometabolic Panel It tests 89 biomarkers Cardiovascular - Apolipoprotein B - Homocysteine - hsCRP - Lipoprotein (a) - Linoleic Acid - Arachidonic Acid - Eicosapentaenoic Acid (EPA) - Docosahexaenoic Acid (DHA) - Docosapentaenoic Acid (DPA) - Omega 6, Total - Omega 3 Total - EPA+DPA+DHA - Omega 6/Omega 3 Ratio - Arachidonic Acid/EPA Ratio - LDL Peak Size - LDL Particle Number - LDL Small - HDL Large - VLDL Size - Triglycerides - Total Cholesterol - HDL Cholesterol - Non-HDL Cholesterol - Total Cholesterol / HDL Ratio Blood - Red Cell Distribution Width (RDW) - Neutrophils (%) - Monocytes (%) - Lymphocytes (%) - Eosinophils (%) - Basophils (%) - Platelet Count - Mean Corpuscular Hemoglobin Concentration (MCHC) - Mean Corpuscular Hemoglobin (MCH) - Mean Corpuscular Volume - Hematocrit - Hemoglobin (HGB) - Band Neutrophils - Blasts - Metamyelocytes - Myelocytes - Nucleated RBC - Promyelocytes - Band Neutrophils (%) - Basophils - Blasts (%) - Eosinophils - Lymphocytes - Metamyelocytes (%) - Monocytes - Myelocytes (%) - Neutrophils - Nucleated RBC (%) - Promyelocytes (%) - Reactive Lymphocytes - Mean Platelet Volume (MPV) - White Blood Cell Count (WBC) - Red Blood Cell Count (RBC) - Protein, Total - HDL P - HDL Size - Large VLDL P - LDL Cholesterol (by calculation) Kidneys - Creatinine - BUN/Creatinine Ratio - Estimated Glomerular Filtration Rate - Calcium - Blood Urea Nitrogen - Carbon Dioxide - Chloride - Potassium - Sodium Liver - Albumin/Globulin Ratio - Total Bilirubin - Globulin (Calculated) - Alkaline Phosphatase (ALP) - Albumin - Aspartate Aminotransferase (AST) - Alanine Aminotransferase (ALT) Metabolic - Glucose (Blood) - Hemoglobin A1c - Uric Acid - Insulin Nutrients - Folate (RBC) - Vitamin B12 (Cobalamin) - Magnesium, RBC - Vitamin D, 25-OH, Total, IA